Application of a UV-vis spectrometer to investigate the effect of dissolution media on the diffusivity of small molecules and proteins

To date, the commonly used methods for diffusion coefficient measurements have some hurdles that prevent them from being widely applied in pharmaceutical laboratories. This study aimed to modify a method developed by di Cagno et al. based on the use of a UV-Vis spectrometer and apply the method to i...

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Veröffentlicht in:Journal of pharmaceutical sciences 2025-01, Vol.114 (1), p.256-264
Hauptverfasser: Lou, Hao, Hu, Gang, Luan, Xi, Steinbach-Rankins, Jill M., Hageman, Michael J.
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Sprache:eng
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