Immune escape between endoplasmic reticulum stress-related cancer cells and exhausted CD8+T cells leads to neoadjuvant chemotherapy resistance in ovarian cancer

Our study aims to explore the effects of neoadjuvant chemotherapy (NACT) on tumour cells and immune cells in the immune microenvironment of patients with high-grade serous ovarian cancer (HGSOC). Single-cell RNA sequencing data of paired ovarian cancer tissues were analysed before and after NACT in...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemical and biophysical research communications 2024-11, Vol.733, p.150686, Article 150686
Hauptverfasser:	Zhang, Siyang, Zhang, Yuli, Song, Xueying, Wang, Xinyi, Quan, Linru, Xu, Pingping, Zhao, Lin, Song, Wei, Liu, Qing, Zhou, Xin
Format:	Artikel
Sprache:	eng
Schlagworte:	Endoplasmic reticulum stress Exhausted CD8+T cell Immune escape Neoadjuvant chemotherapy Ovarian cancer cell
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!