Relationship between mutations in severe hemophilia A and risk of inhibitor development: A large single-center study

One of the major problems for patients with severe hemophilia A (HA) is the development of neutralizing antibodies against factor VIII. This study aimed to analyze the molecular and clinical profiles of patients with severe HA and to determine if certain genetic variants predispose to inhibitor deve...

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Veröffentlicht in:	Transfusion and apheresis science 2024-12, Vol.63 (6), p.104002, Article 104002
Hauptverfasser:	Moghadam, Arash Ahmadfard, Manafzadeh, Amir Reza, Nikoonia, MR, Moazezi, Seyedeh Somayeh, Nekoei, Khadijeh Dajliry, Ramezan, Farahnaz, Bashash, Davood, Hamidpour, Mohsen, Tabibian, Shadi
Format:	Artikel
Sprache:	eng
Schlagworte:	Factor VIII - genetics Female Hemophilia A Hemophilia A - genetics Humans Infant Inhibitor Intron-22 inversion Male Mutation
Online-Zugang:	Volltext
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