Optimization of Polylactide-Co-Glycolide-Rifampicin Nanoparticle Synthesis, In Vitro Study of Mucoadhesion and Drug Release

Despite the large number of works on the synthesis of polylactide-co-glycolide (PLGA) nanoparticles (NP) loaded with antituberculosis drugs, the data on the influence of various factors on the final characteristics of the complexes are quite contradictory. In the present study, a comprehensive analy...

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Veröffentlicht in:	Polymers 2024-08, Vol.16 (17), p.2466
Hauptverfasser:	Yessentayeva, Nazgul A, Galiyeva, Aldana R, Daribay, Arailym T, Sadyrbekov, Daniyar T, Moustafine, Rouslan I, Tazhbayev, Yerkeblan M
Format:	Artikel
Sprache:	eng
Schlagworte:	Dichloromethane Dimethyl sulfoxide Drug delivery systems Efficiency Ethyl acetate Gastrointestinal system Methods Nanoemulsions Nanoparticles Optimization Particle size Poloxamers Polylactic acid Polymers Polyvinyl alcohol Respiration Scanning electron microscopy Solvents Surfactants Synthesis Tuberculosis
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