Mirtazapine Improves Locomotor Activity and Attenuates Neuropathic Pain Following Spinal Cord Injury in Rats via Neuroinflammation Modulation

Neuroinflammation-related locomotor deficits and neuropathic pain are expected outcomes of spinal cord injury (SCI). The atypical antidepressant mirtazapine has exhibited potential neuroprotective and anti-inflammatory effects. This research aims to investigate the impacts of mirtazapine on post-SCI...

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Veröffentlicht in:	Neurochemical research 2024-12, Vol.49 (12), p.3326-3341
Hauptverfasser:	Aghili, Seyed Hadi, Manavi, Mohammad Amin, Panji, Mohammad, Farhang Ranjbar, Mehri, Abrishami, Ramin, Dehpour, Ahmad Reza
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidepressants Attenuation Biochemistry Biomedical and Life Sciences Biomedicine Capsaicin receptors Cell Biology Cytokines Demyelination Down-regulation Filaments Inflammation Interleukins Latency Locomotor activity Neuralgia Neurochemistry Neurology Neuromodulation Neuroprotection Neurosciences Nitric-oxide synthase Original Paper Pain Pain perception Receptors Recovery Spinal cord injuries Staining Tumor necrosis factor-α Western blotting
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