Organoid culture promotes dedifferentiation of mouse myoblasts into stem cells capable of complete muscle regeneration

Experimental cell therapies for skeletal muscle conditions have shown little success, primarily because they use committed myogenic progenitors rather than true muscle stem cells, known as satellite cells. Here we present a method to generate in vitro-derived satellite cells (idSCs) from skeletal mu...

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Veröffentlicht in:	Nature biotechnology 2024-09
Hauptverfasser:	Price, Feodor D, Matyas, Mark N, Gehrke, Andrew R, Chen, William, Wolin, Erica A, Holton, Kristina M, Gibbs, Rebecca M, Lee, Alice, Singu, Pooja S, Sakakeeny, Jeffrey S, Poteracki, James M, Goune, Kelsey, Pfeiffer, Isabella T, Boswell, Sarah A, Sorger, Peter K, Srivastava, Mansi, Pfaff, Kathleen Lindahl, Gussoni, Emanuela, Buchanan, Sean M, Rubin, Lee L
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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