Consensus guidelines for the management of primary central nervous system lymphoma for low and middle-income countries

Primary lymphoma of the central nervous system (PCNSL) is a rare and aggressive form of extranodal non-Hodgkin lymphoma primarily involving the brain, spinal cord, cerebrospinal fluid, and eyes. The role of surgical intervention in PCNSL is currently limited to biopsy and decompression of critical s...

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Veröffentlicht in:Journal of the Pakistan Medical Association 2024-03, Vol.74 (3 (Supple-3)), p.S168
Hauptverfasser: Aziz, Hafiza Fatima, Bakhshi, Saqib Kamran, Ahmed, Noman, Bajwa, Mohammad Hamza, Jabbar, Adnan Abdul, Hafiz, Asim, Gilani, Ahmed, Khalid, Muhammad Usman, Enam, Syed Ather
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container_issue 3 (Supple-3)
container_start_page S168
container_title Journal of the Pakistan Medical Association
container_volume 74
creator Aziz, Hafiza Fatima
Bakhshi, Saqib Kamran
Ahmed, Noman
Bajwa, Mohammad Hamza
Jabbar, Adnan Abdul
Hafiz, Asim
Gilani, Ahmed
Khalid, Muhammad Usman
Enam, Syed Ather
description Primary lymphoma of the central nervous system (PCNSL) is a rare and aggressive form of extranodal non-Hodgkin lymphoma primarily involving the brain, spinal cord, cerebrospinal fluid, and eyes. The role of surgical intervention in PCNSL is currently limited to biopsy and decompression of critical structures if needed - extended resection is debated. Chemotherapy is the mainstay of treatment. In lower and middle-income countries (LMICs), issues like delayed diagnosis and resource constraints are widespread. These guidelines provide a framework for addressing PCNSL in LMICs, emphasizing the importance of early diagnosis, tailored treatment approaches, and ongoing patient monitoring to improve outcomes for this rare and aggressive disease.
doi_str_mv 10.47391/JPMA.S3.GNO-20
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subjects Central Nervous System Neoplasms - diagnosis
Central Nervous System Neoplasms - therapy
Consensus
Developing Countries
Humans
Lymphoma, Non-Hodgkin - diagnosis
Lymphoma, Non-Hodgkin - therapy
Practice Guidelines as Topic
title Consensus guidelines for the management of primary central nervous system lymphoma for low and middle-income countries
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