Corydalis yanhusuo extract and its pharmacological substances alleviate food allergy by inhibiting mast cells activation via PLC/PKC/STAT3 pathway

Food allergies have increasingly become a disease that affects global health and need for corresponding therapeutic drugs urgently. As a traditional Chinses medicine with a wide range of pharmacological effects, however, there was no clear research confirming therapeutic effect and pharmacological s...

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Veröffentlicht in:	Journal of ethnopharmacology 2025-01, Vol.337 (Pt 1), p.118809, Article 118809
Hauptverfasser:	Zhang, Yongjing, Zhang, Wen, Ma, Mengyang, Zhang, Xinping, Li, Chenjia, Deng, Tingting, Gao, Jie, Gao, Chang, Wang, Nan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Allergic Agents - isolation & purification Anti-Allergic Agents - pharmacology Corydaline Corydalis - chemistry Corydalis yanhusuo Food allergy Food Hypersensitivity - drug therapy Male Mast cell Mast Cells - drug effects Mast Cells - metabolism Mice Mice, Inbred BALB C Passive Cutaneous Anaphylaxis - drug effects Plant Extracts - pharmacology Protein Kinase C - metabolism Signal Transduction - drug effects STAT3 Transcription Factor - metabolism Tetrahydropalmatine Type C Phospholipases - metabolism
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