Functional Investigations of p53 Acetylation Enabled by Heterobifunctional Molecules

Post-translational modifications (PTMs) dynamically regulate the critical stress response and tumor suppressive functions of p53. Among these, acetylation events mediated by multiple acetyltransferases lead to differential target gene activation and subsequent cell fate. However, our understanding o...

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Veröffentlicht in:	ACS chemical biology 2024-09, Vol.19 (9), p.1918-1929
Hauptverfasser:	Chen, Li-Yun, Singha Roy, Soumya Jyoti, Jadhav, Appaso M., Wang, Wesley W., Chen, Pei-Hsin, Bishop, Timothy, Erb, Michael A., Parker, Christopher G.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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