Manifesting the Dasatinib-gallic acid co-amorphous system to augment anticancer potential: Physicochemical characterization, in silico molecular simulation, ex vivo permeability, and in vitro efficacy

[Display omitted] Dasatinib (DAB) has been explored for repurposing in the treatment of breast cancer (BC) due to its known effectiveness in treating leukemia, in addition to its role as a tyrosine kinase inhibitor. Gallic acid (GA) was chosen as a co-former due to its anticancer potential in BC, as...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International journal of pharmaceutics 2024-11, Vol.665, p.124672, Article 124672
Hauptverfasser:	Kanp, Tanmoy, Dhuri, Anish, Aalhate, Mayur, Mahajan, Srushti, Munagalasetty, Sharon, Kumar Sah, Sunil, Kaity, Santanu, Sharma, Bhagwati, Bhandari, Vasundhra, Kumar Singh, Pankaj
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Co-amorphous Dasatinib Ex vivo permeability In silico molecular modeling In vitro biological study
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!