A longitudinal study assessing the impact of elexacaftor/tezacaftor/ivacaftor on gut transit and function in people with cystic fibrosis using magnetic resonance imaging (MRI)

•Gut function and transit change following the initiation of ETI, measured using MRI.•Small bowel transit and small bowel response to food improves after starting ETI.•After 18 months of ETI use, colonic volume reduces.•First imaging study to find changes in gut physiology following ETI initiation....

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Veröffentlicht in:Journal of cystic fibrosis 2024-09, Vol.23 (5), p.984-990
Hauptverfasser: Yule, Alexander, Ng, Christabella, Recto, Arantxa, Lockwood, Florence, Dellschaft, Neele S, Hoad, Caroline L, Zagoya, Carlos, Mainz, Jochen G, Major, Giles, Barr, Helen L, Gowland, Penny A, Stewart, Iain, Marciani, Luca, Spiller, Robin C, Smyth, Alan R
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Sprache:eng
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