TXA combined with whole blood transfusion in trauma patients does not increase the risk of VTE but shock index does

Previous studies have demonstrated the benefits of tranexamic acid (TXA) administration in combination with packed red blood cell (PRBC) transfusion in trauma patients without increasing the risk of venous thromboembolism (VTE). However, the effect of TXA in combination with whole blood (WB) has not...

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Veröffentlicht in:	The American journal of surgery 2024-12, Vol.238, p.115931, Article 115931
Hauptverfasser:	Myers, John C., Murphy, Samantha, Limon, David, Gerhardus, Christian, Barry, Lauran, Brigmon, Erika, Eastridge, Brian, Braverman, Maxwell A., Reveles, Kelly, Nicholson, Susannah, Jenkins, Donald
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anticoagulants Antifibrinolytic Agents - administration & dosage Antifibrinolytic Agents - therapeutic use Blood transfusion Blood Transfusion - statistics & numerical data Blood transfusions Cardiovascular disease Combined Modality Therapy Disease prevention Embolism Erythrocyte Transfusion - statistics & numerical data Erythrocytes Female Hemorrhage Hospitals Humans Injuries Injury analysis Injury Severity Score Length of Stay - statistics & numerical data Male Middle Aged Mortality Multivariate analysis Patients Registries Retrospective Studies Risk Factors Shock - etiology Shock - therapy Thromboembolism Thrombosis Tranexamic Acid - administration & dosage Tranexamic Acid - therapeutic use Transfusion Trauma Venous Thromboembolism - epidemiology Venous Thromboembolism - etiology Venous Thromboembolism - prevention & control Wounds and Injuries - complications Wounds and Injuries - therapy
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