The influence of paraventricular nucleus of the hypothalamus soluble guanylate cyclase on autonomic and neuroendocrine responses to acute restraint stress in rats

The paraventricular nucleus of the hypothalamus (PVN) regulates physiological and behavioural responses evoked by stressful stimuli, but the local neurochemical and signalling mechanisms involved are not completely understood. The soluble guanylate cyclase (sGC) within the PVN is implicated in auton...

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Veröffentlicht in:	The European journal of neuroscience 2024-10, Vol.60 (8), p.5849-5860
Hauptverfasser:	Busnardo, Cristiane, Crestani, Carlos C., Fassini, Aline, Scarambone, Bianca M., Packard, Benjamin A., Resstel, Leonardo B. M., Herman, James P., Correa, Fernando M. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autonomic nervous system Autonomic Nervous System - drug effects Autonomic Nervous System - physiopathology Blood pressure Blood Pressure - drug effects Blood Pressure - physiology cardiovascular responses Cardiovascular system Corticosterone Guanylate cyclase Guanylate Cyclase - antagonists & inhibitors Guanylate Cyclase - metabolism Heart Rate - drug effects Heart Rate - physiology Hypothalamic-pituitary-adrenal axis Hypothalamus Male Microinjection Neuroendocrine system Paraventricular Hypothalamic Nucleus - drug effects Paraventricular Hypothalamic Nucleus - metabolism Paraventricular nucleus Pituitary PVN, sGC Rats Rats, Wistar Restraint, Physical Soluble Guanylyl Cyclase - metabolism Stress response Stress, Psychological - metabolism Stress, Psychological - physiopathology sympathetic activity Tachycardia Vasoconstriction
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