18 F‑Fluorination of Nitroimidazolyl-Containing Sultone: A Direct Access to a Highly Hydrophilic Radiotracer for High-Performance Positron Emission Tomography Imaging of Hypoxia

Hypoxia, characterized by nonphysiological levels of oxygen tension, is a key phenomenon common to the majority of malignant tumors with poor prognosis. Many efforts have been made to develop hypoxia imaging for diagnosis, staging, and monitoring of diseases, as well as for evaluating therapies. PET...

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Veröffentlicht in:	JACS Au 2024-08, Vol.4 (8), p.3248-3257
Hauptverfasser:	Maingueneau, Clémence, Lafargue, Anne-Elodie, Guillouet, Stéphane, Fillesoye, Fabien, Cao Pham, Thanh T., Jordan, Bénédicte F., Perrio, Cécile
Format:	Artikel
Sprache:	eng
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