The paravertebral lymphatic system is involved in the resorption of the herniated nucleus pulposus and the regression of inflammation associated with disc herniation

To investigate the role of the paravertebral lymphatic system in the nucleus pulposus herniation (NPH) resorption and the inflammation regression. Clinical specimens (n = 10) from patients with lumbar disc herniation (LDH) were collected, C57BL/6 (n = 84) and conditional Vegfr3 knockout mice (n = 14...

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Veröffentlicht in:	Osteoarthritis and cartilage 2024-12, Vol.32 (12), p.1566-1578
Hauptverfasser:	Fu, Yuanfei, Lan, Zhiming, Li, Ning, Xing, Lianping, Yuan, Luying, Lai, Juyi, Feng, Hualong, Cong, Lin, Wang, Yongjun, He, Shenghua, Liang, Qianqian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Female Humans Inflammation Intervertebral Disc Displacement Lumbar disc herniation Lumbar Vertebrae Lymphangiogenesis - physiology Lymphatic System - pathology Lymphatic Vessels - diagnostic imaging Lymphatic Vessels - pathology Male Mice Mice, Inbred C57BL Mice, Knockout Middle Aged Nucleus Pulposus - metabolism Nucleus Pulposus - pathology Nucleus pulposus herniation Paravertebral lymphatic system Resorption Vascular Endothelial Growth Factor Receptor-3 - genetics Vascular Endothelial Growth Factor Receptor-3 - metabolism
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