Simultaneous Multiparameter Mapping of the Liver in a Single Breath-Hold or Respiratory-Triggered Acquisition Using Multi-Inversion Spin and Gradient Echo MRI

Quantitative parametric mapping is an increasingly important tool for noninvasive assessment of chronic liver disease. Conventional parametric mapping techniques require multiple breath-held acquisitions and provide limited anatomic coverage. To investigate a multi-inversion spin and gradient echo (...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of magnetic resonance imaging 2024-08
Hauptverfasser: Manhard, Mary Kate, Kilpattu Ramaniharan, Anandh, Tkach, Jean A, Trout, Andrew T, Dillman, Jonathan R, Pednekar, Amol S
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title Journal of magnetic resonance imaging
container_volume
creator Manhard, Mary Kate
Kilpattu Ramaniharan, Anandh
Tkach, Jean A
Trout, Andrew T
Dillman, Jonathan R
Pednekar, Amol S
description Quantitative parametric mapping is an increasingly important tool for noninvasive assessment of chronic liver disease. Conventional parametric mapping techniques require multiple breath-held acquisitions and provide limited anatomic coverage. To investigate a multi-inversion spin and gradient echo (MI-SAGE) technique for simultaneous estimation of T , T , and T * of the liver. Prospective. Sixteen research participants, both adult and pediatric (age 17.5 ± 4.6 years, eight male), with and without known liver disease (seven asymptomatic healthy controls, two fibrotic liver disease, five steatotic liver disease, and two fibrotic and steatotic liver disease). 1.5 T, single breath-hold and respiratory triggered MI-SAGE, breath-hold modified Look-Locker inversion recovery (MOLLI, T mapping), breath-hold gradient and spin echo (GRASE, T mapping), and multiple gradient echo (mGRE, T * mapping) sequences. Agreement between hepatic T , T , and T * estimated using MI-SAGE and conventional parametric mapping sequences was evaluated. Repeatability and reproducibility of MI-SAGE were evaluated using a same-session acquisition and second-session acquisition. Bland-Altman analysis with bias assessment and limits of agreement (LOA) and intraclass correlation coefficients (ICC). Hepatic T , T , and T * estimates obtained using the MI-SAGE technique had mean biases of 72 (LOA: -22 to 166) msec, -3 (LOA: -10 to 5) msec, and 2 (LOA: -5 to 8) msec (single breath-hold) and 36 (LOA: -43 to 120) msec, -3 (LOA: -17 to 11) msec, and 4 (LOA: -3 to 11) msec (respiratory triggered), respectively, in comparison to conventional acquisitions using MOLLI, GRASE, and mGRE. All MI-SAGE estimates had strong repeatability and reproducibility (ICC > 0.72). Hepatic T , T , and T * estimates obtained using an MI-SAGE technique were comparable to conventional methods, although there was a 12%/6% for breath-hold/respiratory triggered underestimation of T values compared to MOLLI. Both respiratory triggered and breath-hold MI-SAGE parameter maps demonstrated strong repeatability and reproducibility. 1 TECHNICAL EFFICACY: Stage 2.
doi_str_mv 10.1002/jmri.29584
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_3097851950</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3097851950</sourcerecordid><originalsourceid>FETCH-LOGICAL-p177t-216d99b67c52ecc47512e6b2d15522b52afa661ee5757e39a140c194b7ab37c03</originalsourceid><addsrcrecordid>eNpNkF1rwjAUhsPYmM7tZj9g5HI3dUnaNM2lE6eCMvDjuqTtUSP9MkkH_pn91rXTwa7Oy8PLc-BF6JmSISWEvR0Lo4dM8ii4QX3KGfMYj8Lbf7mHHqw9EkKkDPg96vmSSuZHtI--17pocqdKqBqLl23UtTKqAAcGL1Vd63KPqx12B8AL_dVCXWKF1y3OAb8bUO7gzao8w5XBK7C1NspV5uxtjN7vwUCGR-mp0VY7XZV4azvf7xtvXrY629F13UnLDE-NyjSUDk_SQ4WXq_kjutup3MLT9Q7Q9mOyGc-8xed0Ph4tvJoK4TxGw0zKJBQpZ5CmgeCUQZiwjPJ2goQztVNhSAG44AJ8qWhAUiqDRKjEFynxB-j14q1NdWrAurjQNoU8vwwT-0SKiFPJu-rLtdokBWRxbXShzDn-29T_AcUrejQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3097851950</pqid></control><display><type>article</type><title>Simultaneous Multiparameter Mapping of the Liver in a Single Breath-Hold or Respiratory-Triggered Acquisition Using Multi-Inversion Spin and Gradient Echo MRI</title><source>Wiley Online Library All Journals</source><creator>Manhard, Mary Kate ; Kilpattu Ramaniharan, Anandh ; Tkach, Jean A ; Trout, Andrew T ; Dillman, Jonathan R ; Pednekar, Amol S</creator><creatorcontrib>Manhard, Mary Kate ; Kilpattu Ramaniharan, Anandh ; Tkach, Jean A ; Trout, Andrew T ; Dillman, Jonathan R ; Pednekar, Amol S</creatorcontrib><description>Quantitative parametric mapping is an increasingly important tool for noninvasive assessment of chronic liver disease. Conventional parametric mapping techniques require multiple breath-held acquisitions and provide limited anatomic coverage. To investigate a multi-inversion spin and gradient echo (MI-SAGE) technique for simultaneous estimation of T , T , and T * of the liver. Prospective. Sixteen research participants, both adult and pediatric (age 17.5 ± 4.6 years, eight male), with and without known liver disease (seven asymptomatic healthy controls, two fibrotic liver disease, five steatotic liver disease, and two fibrotic and steatotic liver disease). 1.5 T, single breath-hold and respiratory triggered MI-SAGE, breath-hold modified Look-Locker inversion recovery (MOLLI, T mapping), breath-hold gradient and spin echo (GRASE, T mapping), and multiple gradient echo (mGRE, T * mapping) sequences. Agreement between hepatic T , T , and T * estimated using MI-SAGE and conventional parametric mapping sequences was evaluated. Repeatability and reproducibility of MI-SAGE were evaluated using a same-session acquisition and second-session acquisition. Bland-Altman analysis with bias assessment and limits of agreement (LOA) and intraclass correlation coefficients (ICC). Hepatic T , T , and T * estimates obtained using the MI-SAGE technique had mean biases of 72 (LOA: -22 to 166) msec, -3 (LOA: -10 to 5) msec, and 2 (LOA: -5 to 8) msec (single breath-hold) and 36 (LOA: -43 to 120) msec, -3 (LOA: -17 to 11) msec, and 4 (LOA: -3 to 11) msec (respiratory triggered), respectively, in comparison to conventional acquisitions using MOLLI, GRASE, and mGRE. All MI-SAGE estimates had strong repeatability and reproducibility (ICC &gt; 0.72). Hepatic T , T , and T * estimates obtained using an MI-SAGE technique were comparable to conventional methods, although there was a 12%/6% for breath-hold/respiratory triggered underestimation of T values compared to MOLLI. Both respiratory triggered and breath-hold MI-SAGE parameter maps demonstrated strong repeatability and reproducibility. 1 TECHNICAL EFFICACY: Stage 2.</description><identifier>ISSN: 1522-2586</identifier><identifier>EISSN: 1522-2586</identifier><identifier>DOI: 10.1002/jmri.29584</identifier><identifier>PMID: 39192381</identifier><language>eng</language><publisher>United States</publisher><ispartof>Journal of magnetic resonance imaging, 2024-08</ispartof><rights>2024 The Author(s). Journal of Magnetic Resonance Imaging published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0001-5374-9988 ; 0000-0003-1431-4054 ; 0000-0002-9038-4612 ; 0000-0003-4593-7481 ; 0000-0003-0124-0164</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39192381$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Manhard, Mary Kate</creatorcontrib><creatorcontrib>Kilpattu Ramaniharan, Anandh</creatorcontrib><creatorcontrib>Tkach, Jean A</creatorcontrib><creatorcontrib>Trout, Andrew T</creatorcontrib><creatorcontrib>Dillman, Jonathan R</creatorcontrib><creatorcontrib>Pednekar, Amol S</creatorcontrib><title>Simultaneous Multiparameter Mapping of the Liver in a Single Breath-Hold or Respiratory-Triggered Acquisition Using Multi-Inversion Spin and Gradient Echo MRI</title><title>Journal of magnetic resonance imaging</title><addtitle>J Magn Reson Imaging</addtitle><description>Quantitative parametric mapping is an increasingly important tool for noninvasive assessment of chronic liver disease. Conventional parametric mapping techniques require multiple breath-held acquisitions and provide limited anatomic coverage. To investigate a multi-inversion spin and gradient echo (MI-SAGE) technique for simultaneous estimation of T , T , and T * of the liver. Prospective. Sixteen research participants, both adult and pediatric (age 17.5 ± 4.6 years, eight male), with and without known liver disease (seven asymptomatic healthy controls, two fibrotic liver disease, five steatotic liver disease, and two fibrotic and steatotic liver disease). 1.5 T, single breath-hold and respiratory triggered MI-SAGE, breath-hold modified Look-Locker inversion recovery (MOLLI, T mapping), breath-hold gradient and spin echo (GRASE, T mapping), and multiple gradient echo (mGRE, T * mapping) sequences. Agreement between hepatic T , T , and T * estimated using MI-SAGE and conventional parametric mapping sequences was evaluated. Repeatability and reproducibility of MI-SAGE were evaluated using a same-session acquisition and second-session acquisition. Bland-Altman analysis with bias assessment and limits of agreement (LOA) and intraclass correlation coefficients (ICC). Hepatic T , T , and T * estimates obtained using the MI-SAGE technique had mean biases of 72 (LOA: -22 to 166) msec, -3 (LOA: -10 to 5) msec, and 2 (LOA: -5 to 8) msec (single breath-hold) and 36 (LOA: -43 to 120) msec, -3 (LOA: -17 to 11) msec, and 4 (LOA: -3 to 11) msec (respiratory triggered), respectively, in comparison to conventional acquisitions using MOLLI, GRASE, and mGRE. All MI-SAGE estimates had strong repeatability and reproducibility (ICC &gt; 0.72). Hepatic T , T , and T * estimates obtained using an MI-SAGE technique were comparable to conventional methods, although there was a 12%/6% for breath-hold/respiratory triggered underestimation of T values compared to MOLLI. Both respiratory triggered and breath-hold MI-SAGE parameter maps demonstrated strong repeatability and reproducibility. 1 TECHNICAL EFFICACY: Stage 2.</description><issn>1522-2586</issn><issn>1522-2586</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNpNkF1rwjAUhsPYmM7tZj9g5HI3dUnaNM2lE6eCMvDjuqTtUSP9MkkH_pn91rXTwa7Oy8PLc-BF6JmSISWEvR0Lo4dM8ii4QX3KGfMYj8Lbf7mHHqw9EkKkDPg96vmSSuZHtI--17pocqdKqBqLl23UtTKqAAcGL1Vd63KPqx12B8AL_dVCXWKF1y3OAb8bUO7gzao8w5XBK7C1NspV5uxtjN7vwUCGR-mp0VY7XZV4azvf7xtvXrY629F13UnLDE-NyjSUDk_SQ4WXq_kjutup3MLT9Q7Q9mOyGc-8xed0Ph4tvJoK4TxGw0zKJBQpZ5CmgeCUQZiwjPJ2goQztVNhSAG44AJ8qWhAUiqDRKjEFynxB-j14q1NdWrAurjQNoU8vwwT-0SKiFPJu-rLtdokBWRxbXShzDn-29T_AcUrejQ</recordid><startdate>20240827</startdate><enddate>20240827</enddate><creator>Manhard, Mary Kate</creator><creator>Kilpattu Ramaniharan, Anandh</creator><creator>Tkach, Jean A</creator><creator>Trout, Andrew T</creator><creator>Dillman, Jonathan R</creator><creator>Pednekar, Amol S</creator><scope>NPM</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-5374-9988</orcidid><orcidid>https://orcid.org/0000-0003-1431-4054</orcidid><orcidid>https://orcid.org/0000-0002-9038-4612</orcidid><orcidid>https://orcid.org/0000-0003-4593-7481</orcidid><orcidid>https://orcid.org/0000-0003-0124-0164</orcidid></search><sort><creationdate>20240827</creationdate><title>Simultaneous Multiparameter Mapping of the Liver in a Single Breath-Hold or Respiratory-Triggered Acquisition Using Multi-Inversion Spin and Gradient Echo MRI</title><author>Manhard, Mary Kate ; Kilpattu Ramaniharan, Anandh ; Tkach, Jean A ; Trout, Andrew T ; Dillman, Jonathan R ; Pednekar, Amol S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p177t-216d99b67c52ecc47512e6b2d15522b52afa661ee5757e39a140c194b7ab37c03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Manhard, Mary Kate</creatorcontrib><creatorcontrib>Kilpattu Ramaniharan, Anandh</creatorcontrib><creatorcontrib>Tkach, Jean A</creatorcontrib><creatorcontrib>Trout, Andrew T</creatorcontrib><creatorcontrib>Dillman, Jonathan R</creatorcontrib><creatorcontrib>Pednekar, Amol S</creatorcontrib><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of magnetic resonance imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Manhard, Mary Kate</au><au>Kilpattu Ramaniharan, Anandh</au><au>Tkach, Jean A</au><au>Trout, Andrew T</au><au>Dillman, Jonathan R</au><au>Pednekar, Amol S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Simultaneous Multiparameter Mapping of the Liver in a Single Breath-Hold or Respiratory-Triggered Acquisition Using Multi-Inversion Spin and Gradient Echo MRI</atitle><jtitle>Journal of magnetic resonance imaging</jtitle><addtitle>J Magn Reson Imaging</addtitle><date>2024-08-27</date><risdate>2024</risdate><issn>1522-2586</issn><eissn>1522-2586</eissn><abstract>Quantitative parametric mapping is an increasingly important tool for noninvasive assessment of chronic liver disease. Conventional parametric mapping techniques require multiple breath-held acquisitions and provide limited anatomic coverage. To investigate a multi-inversion spin and gradient echo (MI-SAGE) technique for simultaneous estimation of T , T , and T * of the liver. Prospective. Sixteen research participants, both adult and pediatric (age 17.5 ± 4.6 years, eight male), with and without known liver disease (seven asymptomatic healthy controls, two fibrotic liver disease, five steatotic liver disease, and two fibrotic and steatotic liver disease). 1.5 T, single breath-hold and respiratory triggered MI-SAGE, breath-hold modified Look-Locker inversion recovery (MOLLI, T mapping), breath-hold gradient and spin echo (GRASE, T mapping), and multiple gradient echo (mGRE, T * mapping) sequences. Agreement between hepatic T , T , and T * estimated using MI-SAGE and conventional parametric mapping sequences was evaluated. Repeatability and reproducibility of MI-SAGE were evaluated using a same-session acquisition and second-session acquisition. Bland-Altman analysis with bias assessment and limits of agreement (LOA) and intraclass correlation coefficients (ICC). Hepatic T , T , and T * estimates obtained using the MI-SAGE technique had mean biases of 72 (LOA: -22 to 166) msec, -3 (LOA: -10 to 5) msec, and 2 (LOA: -5 to 8) msec (single breath-hold) and 36 (LOA: -43 to 120) msec, -3 (LOA: -17 to 11) msec, and 4 (LOA: -3 to 11) msec (respiratory triggered), respectively, in comparison to conventional acquisitions using MOLLI, GRASE, and mGRE. All MI-SAGE estimates had strong repeatability and reproducibility (ICC &gt; 0.72). Hepatic T , T , and T * estimates obtained using an MI-SAGE technique were comparable to conventional methods, although there was a 12%/6% for breath-hold/respiratory triggered underestimation of T values compared to MOLLI. Both respiratory triggered and breath-hold MI-SAGE parameter maps demonstrated strong repeatability and reproducibility. 1 TECHNICAL EFFICACY: Stage 2.</abstract><cop>United States</cop><pmid>39192381</pmid><doi>10.1002/jmri.29584</doi><orcidid>https://orcid.org/0000-0001-5374-9988</orcidid><orcidid>https://orcid.org/0000-0003-1431-4054</orcidid><orcidid>https://orcid.org/0000-0002-9038-4612</orcidid><orcidid>https://orcid.org/0000-0003-4593-7481</orcidid><orcidid>https://orcid.org/0000-0003-0124-0164</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1522-2586
ispartof Journal of magnetic resonance imaging, 2024-08
issn 1522-2586
1522-2586
language eng
recordid cdi_proquest_miscellaneous_3097851950
source Wiley Online Library All Journals
title Simultaneous Multiparameter Mapping of the Liver in a Single Breath-Hold or Respiratory-Triggered Acquisition Using Multi-Inversion Spin and Gradient Echo MRI
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T09%3A22%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Simultaneous%20Multiparameter%20Mapping%20of%20the%20Liver%20in%20a%20Single%20Breath-Hold%20or%20Respiratory-Triggered%20Acquisition%20Using%20Multi-Inversion%20Spin%20and%20Gradient%20Echo%20MRI&rft.jtitle=Journal%20of%20magnetic%20resonance%20imaging&rft.au=Manhard,%20Mary%20Kate&rft.date=2024-08-27&rft.issn=1522-2586&rft.eissn=1522-2586&rft_id=info:doi/10.1002/jmri.29584&rft_dat=%3Cproquest_pubme%3E3097851950%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3097851950&rft_id=info:pmid/39192381&rfr_iscdi=true