PDCD4 interacting with PIK3CB and CTSZ promotes the apoptosis of multiple myeloma cells

The role of programmed cell death 4 (PDCD4) in multiple myeloma (MM) development remains unknown. Here, we investigated its role and action mechanism in MM. Bioinformatic analysis indicated that patients with MM and high PDCD4 expression had higher overall survival than those with low PDCD4 expressi...

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Veröffentlicht in:	The FASEB journal 2024-08, Vol.38 (16), p.e70024-n/a
Hauptverfasser:	Liu, Liyuan, Feng, Xiumei, Fan, Chenliu, Kong, Dexiao, Feng, Xiaoli, Sun, Chenxi, Xu, Yaqi, Li, Binggen, Jiang, Yang, Zheng, Chengyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis Regulatory Proteins - genetics Apoptosis Regulatory Proteins - metabolism Cathepsin Z Cell Line, Tumor Class I Phosphatidylinositol 3-Kinases - genetics Class I Phosphatidylinositol 3-Kinases - metabolism Gene Expression Regulation, Neoplastic Humans Male Mice multiple myeloma Multiple Myeloma - genetics Multiple Myeloma - metabolism Multiple Myeloma - pathology PIK3CB programmed cell death 4 RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism X-Linked Inhibitor of Apoptosis Protein - genetics X-Linked Inhibitor of Apoptosis Protein - metabolism
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