KGF‐2 ameliorates UVB‐triggered skin photodamage in mice by attenuating DNA damage and inflammatory response and mitochondrial dysfunction

Background Long‐term exposure to UVB induces DNA damage, inflammatory response, mitochondrial dysfunction, and apoptosis in skin cells, thus causing skin photodamage. Research has demonstrated the noteworthy antioxidant, anti‐inflammatory, DNA repair, and mitochondrial protective properties of kerat...

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Veröffentlicht in:	Photodermatology, photoimmunology & photomedicine photoimmunology & photomedicine, 2024-09, Vol.40 (5), p.e12993-n/a
Hauptverfasser:	Li, Xuenan, Cheng, Jinli, Guo, Keke, Wan, Jianwei, Wang, Cuihong, Chen, Lu, Xu, Nuo, Chen, Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects DNA damage DNA Damage - drug effects Female Fibroblast Growth Factor 7 - pharmacology Inflammation - pathology inflammatory response keratinocyte growth factor‐2 Mice Mitochondria - drug effects Mitochondria - metabolism Mitochondria - pathology mitochondrial dysfunction Skin - drug effects Skin - metabolism Skin - pathology Skin - radiation effects skin photodamage ultraviolet B radiation Ultraviolet Rays - adverse effects
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