Exploration of the potential mechanism of aqueous extract of Artemisia capillaris for the treatment of non-alcoholic fatty liver disease based on network pharmacology and experimental verification

Abstract Objectives Non-alcoholic fatty liver disease (NAFLD) is a nutritional and metabolic disease with a high prevalence today. Artemisia capillaris has anti-inflammatory, antioxidant, and other effects. However, the mechanism of A. capillaris in treating NAFLD is still poorly understood. Methods...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 2024-10, Vol.76 (10), p.1328-1339
Hauptverfasser:	Liang, Meng, Dong, Siyu, Guo, Yi, Zhang, Yuyi, Xiao, Xiao, Ma, Jun, Jiang, Xiaowen, Yu, Wenhui
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Artemisia - chemistry Diet, High-Fat - adverse effects Disease Models, Animal Hep G2 Cells Humans Lipid Metabolism - drug effects Liver - drug effects Liver - metabolism Male Mice Mice, Inbred C57BL Molecular Docking Simulation Network Pharmacology Non-alcoholic Fatty Liver Disease - drug therapy Plant Extracts - pharmacology
Online-Zugang:	Volltext
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