Using machine learning to dissect host kinases required for Leishmania internalization and development

The Leishmania life cycle alternates between promastigotes, found in the sandfly, and amastigotes, found in mammals. When an infected sandfly bites a host, promastigotes are engulfed by phagocytes (i.e., neutrophils, dendritic cells, and macrophages) to establish infection. When these phagocytes die...

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Veröffentlicht in:Molecular and biochemical parasitology 2024-12, Vol.260, p.111651, Article 111651
Hauptverfasser: Wei, Ling, Barrie, Umaru, Aloisio, Gina M., Khuong, Francis T.H., Arang, Nadia, Datta, Arani, Kaushansky, Alexis, Wetzel, Dawn M.
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Sprache:eng
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