TBHP Promotes Cross-Dehydrogenative Coupling of SF4 Alkynes with Tetrahydroisoquinolines under Copper Catalysis

We present a viable approach for the cross-dehydrogenative coupling of Het-SF4-alkynes with tetrahydroisoquinolines under oxidative conditions, using TBHP and copper catalysts. These newly developed conditions boast enhanced yields and a more extensive range of substrates, demonstrating tolerance to...

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Veröffentlicht in:	Organic letters 2024-09, Vol.26 (35), p.7370-7375
Hauptverfasser:	Narra, Srikanth Reddy, Ariff, Putri Nur Arina Mohd, Saha, Debarshi, Bacho, Muhamad Zulfaqar, Shibata, Norio
Format:	Artikel
Sprache:	eng
Schlagworte:	alkynes catalytic activity drugs tetrahydroisoquinolines
Online-Zugang:	Volltext
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