Quality of Life is an Independent Predictor of Mortality in Patients with Heart Failure: A Prospective Cohort Study from the Colombian Heart Failure Registry (RECOLFACA)
Patients with Heart Failure (HF) commonly have poor quality of life (QoL), secondary to the persistence and severity of HF symptoms. We aimed to evaluate the prognostic value of QoL measures on all-cause mortality in patients with HF from the Colombian registry of heart failure (RECOLFACA). We analy...
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| Veröffentlicht in: | European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology 2024-08 |
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| creator | Gómez-Mesa, Juan Esteban Luna-Bonilla, Paula Echeverría, Luis Eduardo Rivera-Toquica, Alex Jurado-Arenales, Adriana Milena Orozco, María Johanna Buitrago-Malaver, Lilia Andrea Rivera, Edilma L González, Diana Verónica Coronado-Villa, Estefanny Toro-Cardona, Olga Cristina López-Montes, Cristian Alexander Vargas-Márquez, Ludy Yanet Martínez-Camargo, Silvia Agudelo-Pérez, Adriana Vivas-Mayor, Marcela Niño, Lina María Mejía-Cadavid, Luz Aida Aponte-Romero, Luisa Fernanda Erazo, María José García-Barrera, María Meza-Roque, Julio Armando Ríos-Sánchez, Viviana Torres-Moreno, Fabián Castañeda-M, Jenny Gallego, Cesar A Martínez, Fanny Esther Blandón-Córdoba, Carmen Jineth Silva-Carmona, Mónica Saldarriaga, Clara |
| description | Patients with Heart Failure (HF) commonly have poor quality of life (QoL), secondary to the persistence and severity of HF symptoms. We aimed to evaluate the prognostic value of QoL measures on all-cause mortality in patients with HF from the Colombian registry of heart failure (RECOLFACA).
We analyzed data from patients registered in RECOLFACA during 2017-2019. QoL was measured using the EuroQol-5D questionnaire (EQ-5D). From the questionnaire, two independent predictors of mortality were obtained, the visual analogue scale (VAS) and the utility score (US). Primary outcome was all-cause mortality, and secondary variables evaluated were demographic factors, comorbidities, NYHA classification, medications used and laboratory test results. To analyze survival among patients, the Kaplan-Meier method and the hierarchical Cox proportional-hazards regression model were used. This study included 2514 patients from RECOLFACA. Most patients were male (57.6%), and mean age was 67.8 years. Mean value and standard deviation (SD) of the VAS score was 78.8 ± 20.1 points, while the mean and SD of the US score was 0.81 ± 0.20. As the Kaplan-Meier curve illustrated, patients in the lower quartiles of both VAS and US scores had a significantly higher probability of mortality (log-rank test: p |
| doi_str_mv | 10.1093/eurjcn/zvae117 |
| format | Article |
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We analyzed data from patients registered in RECOLFACA during 2017-2019. QoL was measured using the EuroQol-5D questionnaire (EQ-5D). From the questionnaire, two independent predictors of mortality were obtained, the visual analogue scale (VAS) and the utility score (US). Primary outcome was all-cause mortality, and secondary variables evaluated were demographic factors, comorbidities, NYHA classification, medications used and laboratory test results. To analyze survival among patients, the Kaplan-Meier method and the hierarchical Cox proportional-hazards regression model were used. This study included 2514 patients from RECOLFACA. Most patients were male (57.6%), and mean age was 67.8 years. Mean value and standard deviation (SD) of the VAS score was 78.8 ± 20.1 points, while the mean and SD of the US score was 0.81 ± 0.20. As the Kaplan-Meier curve illustrated, patients in the lower quartiles of both VAS and US scores had a significantly higher probability of mortality (log-rank test: p<0.001 for both scores).
QoL, as calculated by the EQ-5D questionnaire, served as an independent predictor of mortality in patients from RECOLFACA. Further studies may be needed to evaluate whether provision of optimizing therapies and follow-up care based on patients' perceived QoL reduces short- and long-term mortality rates in this population.</description><identifier>ISSN: 1474-5151</identifier><identifier>ISSN: 1873-1953</identifier><identifier>EISSN: 1873-1953</identifier><identifier>DOI: 10.1093/eurjcn/zvae117</identifier><identifier>PMID: 39177271</identifier><language>eng</language><publisher>England</publisher><ispartof>European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology, 2024-08</ispartof><rights>The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c180t-28238f148f67fac832af3784cdda53b9d8ff7873507585a88d02ee55fcabf6f43</cites><orcidid>0009-0006-4786-2291 ; 0009-0002-6021-4724 ; 0000-0002-7056-2813 ; 0000-0002-3147-0975 ; 0009-0000-2673-0448 ; 0000-0003-0866-2677 ; 0009-0000-8511-7969 ; 0009-0006-2859-7795 ; 0009-0003-4454-9388 ; 0009-0005-3448-0537 ; 0000-0001-8201-0322 ; 0009-0007-3857-1027 ; 0009-0005-2749-4404 ; 0000-0002-5945-1127 ; 0000-0002-6635-6224 ; 0009-0004-2089-4539 ; 0000-0002-4642-4162 ; 0009-0003-7765-4475 ; 0000-0001-5784-3859 ; 0009-0002-4992-3116 ; 0000-0002-0143-4885 ; 0000-0002-3137-8319 ; 0009-0004-8098-443X ; 0009-0007-4169-3949 ; 0009-0000-5335-5743 ; 0009-0006-4628-547X ; 0000-0002-1532-5778 ; 0009-0009-8144-9742 ; 0000-0001-8293-789X ; 0009-0005-9483-5918</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39177271$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gómez-Mesa, Juan Esteban</creatorcontrib><creatorcontrib>Luna-Bonilla, Paula</creatorcontrib><creatorcontrib>Echeverría, Luis Eduardo</creatorcontrib><creatorcontrib>Rivera-Toquica, Alex</creatorcontrib><creatorcontrib>Jurado-Arenales, Adriana Milena</creatorcontrib><creatorcontrib>Orozco, María Johanna</creatorcontrib><creatorcontrib>Buitrago-Malaver, Lilia Andrea</creatorcontrib><creatorcontrib>Rivera, Edilma L</creatorcontrib><creatorcontrib>González, Diana Verónica</creatorcontrib><creatorcontrib>Coronado-Villa, Estefanny</creatorcontrib><creatorcontrib>Toro-Cardona, Olga Cristina</creatorcontrib><creatorcontrib>López-Montes, Cristian Alexander</creatorcontrib><creatorcontrib>Vargas-Márquez, Ludy Yanet</creatorcontrib><creatorcontrib>Martínez-Camargo, Silvia</creatorcontrib><creatorcontrib>Agudelo-Pérez, Adriana</creatorcontrib><creatorcontrib>Vivas-Mayor, Marcela</creatorcontrib><creatorcontrib>Niño, Lina María</creatorcontrib><creatorcontrib>Mejía-Cadavid, Luz Aida</creatorcontrib><creatorcontrib>Aponte-Romero, Luisa Fernanda</creatorcontrib><creatorcontrib>Erazo, María José</creatorcontrib><creatorcontrib>García-Barrera, María</creatorcontrib><creatorcontrib>Meza-Roque, Julio Armando</creatorcontrib><creatorcontrib>Ríos-Sánchez, Viviana</creatorcontrib><creatorcontrib>Torres-Moreno, Fabián</creatorcontrib><creatorcontrib>Castañeda-M, Jenny</creatorcontrib><creatorcontrib>Gallego, Cesar A</creatorcontrib><creatorcontrib>Martínez, Fanny Esther</creatorcontrib><creatorcontrib>Blandón-Córdoba, Carmen Jineth</creatorcontrib><creatorcontrib>Silva-Carmona, Mónica</creatorcontrib><creatorcontrib>Saldarriaga, Clara</creatorcontrib><title>Quality of Life is an Independent Predictor of Mortality in Patients with Heart Failure: A Prospective Cohort Study from the Colombian Heart Failure Registry (RECOLFACA)</title><title>European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology</title><addtitle>Eur J Cardiovasc Nurs</addtitle><description>Patients with Heart Failure (HF) commonly have poor quality of life (QoL), secondary to the persistence and severity of HF symptoms. We aimed to evaluate the prognostic value of QoL measures on all-cause mortality in patients with HF from the Colombian registry of heart failure (RECOLFACA).
We analyzed data from patients registered in RECOLFACA during 2017-2019. QoL was measured using the EuroQol-5D questionnaire (EQ-5D). From the questionnaire, two independent predictors of mortality were obtained, the visual analogue scale (VAS) and the utility score (US). Primary outcome was all-cause mortality, and secondary variables evaluated were demographic factors, comorbidities, NYHA classification, medications used and laboratory test results. To analyze survival among patients, the Kaplan-Meier method and the hierarchical Cox proportional-hazards regression model were used. This study included 2514 patients from RECOLFACA. Most patients were male (57.6%), and mean age was 67.8 years. Mean value and standard deviation (SD) of the VAS score was 78.8 ± 20.1 points, while the mean and SD of the US score was 0.81 ± 0.20. As the Kaplan-Meier curve illustrated, patients in the lower quartiles of both VAS and US scores had a significantly higher probability of mortality (log-rank test: p<0.001 for both scores).
QoL, as calculated by the EQ-5D questionnaire, served as an independent predictor of mortality in patients from RECOLFACA. 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We aimed to evaluate the prognostic value of QoL measures on all-cause mortality in patients with HF from the Colombian registry of heart failure (RECOLFACA).
We analyzed data from patients registered in RECOLFACA during 2017-2019. QoL was measured using the EuroQol-5D questionnaire (EQ-5D). From the questionnaire, two independent predictors of mortality were obtained, the visual analogue scale (VAS) and the utility score (US). Primary outcome was all-cause mortality, and secondary variables evaluated were demographic factors, comorbidities, NYHA classification, medications used and laboratory test results. To analyze survival among patients, the Kaplan-Meier method and the hierarchical Cox proportional-hazards regression model were used. This study included 2514 patients from RECOLFACA. Most patients were male (57.6%), and mean age was 67.8 years. Mean value and standard deviation (SD) of the VAS score was 78.8 ± 20.1 points, while the mean and SD of the US score was 0.81 ± 0.20. As the Kaplan-Meier curve illustrated, patients in the lower quartiles of both VAS and US scores had a significantly higher probability of mortality (log-rank test: p<0.001 for both scores).
QoL, as calculated by the EQ-5D questionnaire, served as an independent predictor of mortality in patients from RECOLFACA. Further studies may be needed to evaluate whether provision of optimizing therapies and follow-up care based on patients' perceived QoL reduces short- and long-term mortality rates in this population.</abstract><cop>England</cop><pmid>39177271</pmid><doi>10.1093/eurjcn/zvae117</doi><orcidid>https://orcid.org/0009-0006-4786-2291</orcidid><orcidid>https://orcid.org/0009-0002-6021-4724</orcidid><orcidid>https://orcid.org/0000-0002-7056-2813</orcidid><orcidid>https://orcid.org/0000-0002-3147-0975</orcidid><orcidid>https://orcid.org/0009-0000-2673-0448</orcidid><orcidid>https://orcid.org/0000-0003-0866-2677</orcidid><orcidid>https://orcid.org/0009-0000-8511-7969</orcidid><orcidid>https://orcid.org/0009-0006-2859-7795</orcidid><orcidid>https://orcid.org/0009-0003-4454-9388</orcidid><orcidid>https://orcid.org/0009-0005-3448-0537</orcidid><orcidid>https://orcid.org/0000-0001-8201-0322</orcidid><orcidid>https://orcid.org/0009-0007-3857-1027</orcidid><orcidid>https://orcid.org/0009-0005-2749-4404</orcidid><orcidid>https://orcid.org/0000-0002-5945-1127</orcidid><orcidid>https://orcid.org/0000-0002-6635-6224</orcidid><orcidid>https://orcid.org/0009-0004-2089-4539</orcidid><orcidid>https://orcid.org/0000-0002-4642-4162</orcidid><orcidid>https://orcid.org/0009-0003-7765-4475</orcidid><orcidid>https://orcid.org/0000-0001-5784-3859</orcidid><orcidid>https://orcid.org/0009-0002-4992-3116</orcidid><orcidid>https://orcid.org/0000-0002-0143-4885</orcidid><orcidid>https://orcid.org/0000-0002-3137-8319</orcidid><orcidid>https://orcid.org/0009-0004-8098-443X</orcidid><orcidid>https://orcid.org/0009-0007-4169-3949</orcidid><orcidid>https://orcid.org/0009-0000-5335-5743</orcidid><orcidid>https://orcid.org/0009-0006-4628-547X</orcidid><orcidid>https://orcid.org/0000-0002-1532-5778</orcidid><orcidid>https://orcid.org/0009-0009-8144-9742</orcidid><orcidid>https://orcid.org/0000-0001-8293-789X</orcidid><orcidid>https://orcid.org/0009-0005-9483-5918</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1474-5151 |
| ispartof | European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology, 2024-08 |
| issn | 1474-5151 1873-1953 1873-1953 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_3096286464 |
| source | Oxford University Press Journals All Titles (1996-Current) |
| title | Quality of Life is an Independent Predictor of Mortality in Patients with Heart Failure: A Prospective Cohort Study from the Colombian Heart Failure Registry (RECOLFACA) |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T22%3A31%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Quality%20of%20Life%20is%20an%20Independent%20Predictor%20of%20Mortality%20in%20Patients%20with%20Heart%20Failure:%20A%20Prospective%20Cohort%20Study%20from%20the%20Colombian%20Heart%20Failure%20Registry%20(RECOLFACA)&rft.jtitle=European%20journal%20of%20cardiovascular%20nursing%20:%20journal%20of%20the%20Working%20Group%20on%20Cardiovascular%20Nursing%20of%20the%20European%20Society%20of%20Cardiology&rft.au=G%C3%B3mez-Mesa,%20Juan%20Esteban&rft.date=2024-08-23&rft.issn=1474-5151&rft.eissn=1873-1953&rft_id=info:doi/10.1093/eurjcn/zvae117&rft_dat=%3Cproquest_cross%3E3096286464%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3096286464&rft_id=info:pmid/39177271&rfr_iscdi=true |