Altered epitopes enhance macrophage‐mediated anti‐tumour immunity to low‐immunogenic tumour mutations

Personalized neoantigen therapy has shown long‐term and stable efficacy in specific patient populations. However, not all patients have sufficient levels of neoantigens for treatment. Although somatic mutations are commonly found in tumours, a significant portion of these mutations do not trigger an...

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Veröffentlicht in:Immunology 2024-12, Vol.173 (4), p.654-671
Hauptverfasser: Yu, Qiumin, Zhang, Tingran, He, Tiandi, Yang, Yifan, Zhang, Wanli, Kang, Yanliang, Wu, Zijie, Xie, Wenbin, Zheng, Jiaxue, Qian, Qianqian, Li, Guozhi, Zhang, Di, Mao, Qiuli, Gao, Zheng, Wang, Xiaoning, Shi, Xupeiyao, Huang, Shitong, Guo, Hanlin, Zhang, Haoyu, Chen, Lingxiao, Li, Ximing, Deng, Danni, Zhang, Li, Tong, Yue, Yao, Wenbing, Gao, Xiangdong, Tian, Hong
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Sprache:eng
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