Astragaloside IV inhibits the proliferation, migration, invasion, and epithelial-mesenchymal transition of oral cancer cells by aggravating autophagy

Oral cancer is one usual tumor that sorely affects the health of people and even result into death. Astragaloside IV (AS-IV) is one of the major components of Astragalus membranaceus extract, and has been identified to exhibit ameliorative functions in some cancers. Nevertheless, the regulatory impa...

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Veröffentlicht in:	Tissue & cell 2024-10, Vol.90, p.102524, Article 102524
Hauptverfasser:	Yin, Weijia, Liao, Xiangling, Sun, Jieli, Chen, Qu, Fan, Shan
Format:	Artikel
Sprache:	eng
Schlagworte:	Astragaloside IV Autophagy Autophagy - drug effects Cell Growth Processes - drug effects Cell Line, Tumor Cell Movement - drug effects Dose-Response Relationship, Drug Epithelial-Mesenchymal Transition - drug effects Humans Mouth Neoplasms - drug therapy Oral cancer Saponins - pharmacology Signal Transduction - drug effects The AMPK and AKT/mTOR pathways Triterpenes - pharmacology
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