Bridging pyrimidine hemicurcumin and Cisplatin: Synthesis, coordination chemistry, and in vitro activity assessment of a novel Pt(II) complex

In the upcoming decades, the incidence and mortality rates of cancer are expected to rise globally, with colorectal and prostate cancers among the most prevalent types. Despite advancements in molecular targeted therapy, platinum-based chemotherapies remain the cornerstone of treatment, especially f...

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Veröffentlicht in:	Journal of inorganic biochemistry 2024-11, Vol.260, p.112702, Article 112702
Hauptverfasser:	Mari, Matteo, Boniburini, Matteo, Tosato, Marianna, Zanni, Francesca, Bonini, Filippo, Faglioni, Francesco, Cuoghi, Laura, Belluti, Silvia, Imbriano, Carol, Asti, Mattia, Ferrari, Erika
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino-pyrimidine Curcumin derivatives Density Functional theory Nuclear Magnetic Resonance Oxaliplatin Platinum-based drugs
Online-Zugang:	Volltext
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