Neonatal overfeeding promotes anxiety, impairs episodic-like memory, and disrupts transcriptional regulation of hippocampal steroidogenic enzymes

•Small litter affects metabolic parameters.•Small litter impairs episodic like-memory.•Small litter increases anxiety-like behavior.•Small litter dysregulates neurosteroidogenic enzyme expression.•Alterations in enzyme expression are correlated with changes in methylation patterns. The objective of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of nutritional biochemistry 2024-12, Vol.134, p.109739, Article 109739
Hauptverfasser:	Rossetti, Maria Florencia, Schumacher, Rocio, Canesini, Guillermina, Fernandez, Pamela, Gaydou, Luisa, Stoker, Cora, Ramos, Jorge Guillermo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Anxiety Aromatase - genetics Aromatase - metabolism Behavior DNA methylation Female Hippocampus - metabolism Hyperphagia - metabolism Male Memory, Episodic Neuroesteroidogenic enzymes Overnutrition - metabolism Postnatal programming Rats Rats, Sprague-Dawley Small litter
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!