Mitochondrial bioenergetic dysfunction linked to myxomatous mitral valve degeneration explored by PBMCs metabolism analysis

Impaired mitochondria cause an impressive decrease in ATP production becoming a common condition of cardiovascular diseases. Myxomatous mitral valve disease (MMVD) is characterized by mitochondrial dysfunction. By a non-invasive procedure of metabolism analysis on peripheral blood mononuclear cells,...

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Veröffentlicht in:	Biochimica et biophysica acta. Bioenergetics 2024-11, Vol.1865 (4), p.149505, Article 149505
Hauptverfasser:	Granata, Silvia, Bernardini, Chiara, Glogowski, Patrycja Anna, Romito, Giovanni, Salaroli, Roberta, Algieri, Cristina, Cugliari, Antonia, Fabbri, Micaela, Trombetti, Fabiana, Zannoni, Augusta, Nesci, Salvatore
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Aged ATP production Bioenergetics Cell metabolism Energy Metabolism Female Glycolysis Humans Leukocytes, Mononuclear - metabolism Male Middle Aged Mitochondria Mitochondria - metabolism Mitochondria - pathology Mitral Valve - metabolism Mitral Valve - pathology Myxomatous mitral valve disease
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