Synthesis and Characterization of Copper‐Crosslinked Carbon Dot Nanoassemblies for Efficient Macrophage Manipulation

Nanomedicines loaded in macrophages (MAs) can actively target tumors without dominantly relying on the enhanced permeability and retention (EPR) effect, making them effective for treating EPR‐deficient malignancies. Herein, copper‐crosslinked carbon dot clusters (CDCs) are synthesized with both phot...

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Veröffentlicht in:	Macromolecular rapid communications. 2024-11, Vol.45 (22), p.e2400511-n/a
Hauptverfasser:	Girma, Wubshet Mekonnen, Zhu, Zewen, Guo, Yunqi, Xiao, Xianghao, Wang, Zhiqiang, Mekuria, Shewaye Lakew, Hameed, Meera Moydeen Abdul, EL‐Newehy, Mohamed, Guo, Rui, Shen, Mingwu, Shi, Xiangyang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carbon Carbon - chemistry Carbon dots Copper Copper - chemistry Cross-Linking Reagents - chemistry Crosslinking Depletion Fluorescence Glutathione Glutathione - chemistry GSH depletion Humans Irradiation Laser radiation macrophage M1 polarization Macrophages Macrophages - metabolism Malignancy Mice nanoassemblies Particle Size Phenotypes Photochemotherapy Photodynamic therapy Polarization Quantum Dots - chemistry RAW 264.7 Cells Reactive oxygen species Reactive Oxygen Species - metabolism ROS generation Tumor microenvironment Tumors
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