The public health and economic burden of long COVID in Australia, 2022–24: a modelling study

Objective To estimate the number of people in Australia with long COVID by age group, and the associated medium term productivity and economic losses. Study design Modelling study: a susceptible–exposed–infected–recovered (SEIR) model to estimate the number of people with long COVID over time follow...

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Veröffentlicht in:Medical journal of Australia 2024-08, Vol.221 (4), p.217-223
Hauptverfasser: Costantino, Valentina, Grafton, Quentin, Kompas, Tom, Chu, Long, Honeyman, Damian, Notaras, Adriana, MacIntyre, C Raina
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container_end_page 223
container_issue 4
container_start_page 217
container_title Medical journal of Australia
container_volume 221
creator Costantino, Valentina
Grafton, Quentin
Kompas, Tom
Chu, Long
Honeyman, Damian
Notaras, Adriana
MacIntyre, C Raina
description Objective To estimate the number of people in Australia with long COVID by age group, and the associated medium term productivity and economic losses. Study design Modelling study: a susceptible–exposed–infected–recovered (SEIR) model to estimate the number of people with long COVID over time following single infections, and a labour supply model to estimate productivity losses as a proportion of gross domestic product (GDP). Setting Australia, 2022–2024. Main outcome measures Estimated number of people infected with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) during 2022–2023 (based on serosurvey data) who have long COVID, 2022–2024, by age group; estimated GDP loss during 2022 caused by reduced labour supply attributable to long COVID. Results Our model projected that the number of people with long COVID following a single infection in 2022 would peak in September 2022, when 310 341–1 374 805 people (1.2–5.4% of Australians) would have symptoms of long COVID, declining to 172 530–872 799 people (0.7–3.4%) in December 2024, including 7902–30 002 children aged 0–4 years (0.6–2.2%). The estimated mean labour loss attributable to long COVID in 2022 was projected to be 102.4 million (95% confidence interval [CI], 50.4–162.2 million) worked hours, equivalent to 0.48% (95% CI, 0.24–0.76%) of total worked hours in Australia during the 2020–21 financial year. The estimated mean GDP loss caused by the projected decline in labour supply and reduced use of other production factors was $9.6 billion (95% CI, $4.7–15.2 billion), or 0.5% of GDP. The estimated labour loss was greatest for people aged 30–39 years (27.5 million [95% CI, 16.0–41.0 million] hours; 26.9% of total labour loss) and people aged 40–49 years (24.5 million [95% CI, 12.1–38.7 million] hours; 23.9% of total labour loss). Conclusion Widespread SARS‐CoV‐2 infections in Australia mean that even a small proportion of infected people developing long COVID‐related illness and disability could have important population health and economic effects. A paradigm shift is needed, from a sole focus on the immediate effects of coronavirus disease 2019 (COVID‐19) to preventing and treating COVID‐19 and treating long COVID, with implications for vaccine and antiviral policy and other mitigation of COVID‐19.
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Study design Modelling study: a susceptible–exposed–infected–recovered (SEIR) model to estimate the number of people with long COVID over time following single infections, and a labour supply model to estimate productivity losses as a proportion of gross domestic product (GDP). Setting Australia, 2022–2024. Main outcome measures Estimated number of people infected with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) during 2022–2023 (based on serosurvey data) who have long COVID, 2022–2024, by age group; estimated GDP loss during 2022 caused by reduced labour supply attributable to long COVID. Results Our model projected that the number of people with long COVID following a single infection in 2022 would peak in September 2022, when 310 341–1 374 805 people (1.2–5.4% of Australians) would have symptoms of long COVID, declining to 172 530–872 799 people (0.7–3.4%) in December 2024, including 7902–30 002 children aged 0–4 years (0.6–2.2%). The estimated mean labour loss attributable to long COVID in 2022 was projected to be 102.4 million (95% confidence interval [CI], 50.4–162.2 million) worked hours, equivalent to 0.48% (95% CI, 0.24–0.76%) of total worked hours in Australia during the 2020–21 financial year. The estimated mean GDP loss caused by the projected decline in labour supply and reduced use of other production factors was $9.6 billion (95% CI, $4.7–15.2 billion), or 0.5% of GDP. The estimated labour loss was greatest for people aged 30–39 years (27.5 million [95% CI, 16.0–41.0 million] hours; 26.9% of total labour loss) and people aged 40–49 years (24.5 million [95% CI, 12.1–38.7 million] hours; 23.9% of total labour loss). Conclusion Widespread SARS‐CoV‐2 infections in Australia mean that even a small proportion of infected people developing long COVID‐related illness and disability could have important population health and economic effects. A paradigm shift is needed, from a sole focus on the immediate effects of coronavirus disease 2019 (COVID‐19) to preventing and treating COVID‐19 and treating long COVID, with implications for vaccine and antiviral policy and other mitigation of COVID‐19.</description><identifier>ISSN: 0025-729X</identifier><identifier>ISSN: 1326-5377</identifier><identifier>EISSN: 1326-5377</identifier><identifier>DOI: 10.5694/mja2.52400</identifier><identifier>PMID: 39154292</identifier><language>eng</language><publisher>Australia</publisher><subject>Adolescent ; Adult ; Aged ; Australia - epidemiology ; Child ; Child, Preschool ; Cost of Illness ; COVID-19 - economics ; COVID-19 - epidemiology ; Female ; Gross Domestic Product ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Post-Acute COVID-19 Syndrome ; Public Health - economics ; SARS-CoV-2 ; Young Adult</subject><ispartof>Medical journal of Australia, 2024-08, Vol.221 (4), p.217-223</ispartof><rights>2024 The Author(s). published by John Wiley &amp; Sons Australia, Ltd on behalf of AMPCo Pty Ltd.</rights><rights>2024 The Author(s). Medical Journal of Australia published by John Wiley &amp; Sons Australia, Ltd on behalf of AMPCo Pty Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c2180-992b88cb5c8bbf8d1480cea57294d047b136d09e48a18254667cd4500a10ee353</cites><orcidid>0000-0001-6017-4430</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.5694%2Fmja2.52400$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.5694%2Fmja2.52400$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39154292$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Costantino, Valentina</creatorcontrib><creatorcontrib>Grafton, Quentin</creatorcontrib><creatorcontrib>Kompas, Tom</creatorcontrib><creatorcontrib>Chu, Long</creatorcontrib><creatorcontrib>Honeyman, Damian</creatorcontrib><creatorcontrib>Notaras, Adriana</creatorcontrib><creatorcontrib>MacIntyre, C Raina</creatorcontrib><title>The public health and economic burden of long COVID in Australia, 2022–24: a modelling study</title><title>Medical journal of Australia</title><addtitle>Med J Aust</addtitle><description>Objective To estimate the number of people in Australia with long COVID by age group, and the associated medium term productivity and economic losses. Study design Modelling study: a susceptible–exposed–infected–recovered (SEIR) model to estimate the number of people with long COVID over time following single infections, and a labour supply model to estimate productivity losses as a proportion of gross domestic product (GDP). Setting Australia, 2022–2024. Main outcome measures Estimated number of people infected with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) during 2022–2023 (based on serosurvey data) who have long COVID, 2022–2024, by age group; estimated GDP loss during 2022 caused by reduced labour supply attributable to long COVID. Results Our model projected that the number of people with long COVID following a single infection in 2022 would peak in September 2022, when 310 341–1 374 805 people (1.2–5.4% of Australians) would have symptoms of long COVID, declining to 172 530–872 799 people (0.7–3.4%) in December 2024, including 7902–30 002 children aged 0–4 years (0.6–2.2%). The estimated mean labour loss attributable to long COVID in 2022 was projected to be 102.4 million (95% confidence interval [CI], 50.4–162.2 million) worked hours, equivalent to 0.48% (95% CI, 0.24–0.76%) of total worked hours in Australia during the 2020–21 financial year. The estimated mean GDP loss caused by the projected decline in labour supply and reduced use of other production factors was $9.6 billion (95% CI, $4.7–15.2 billion), or 0.5% of GDP. The estimated labour loss was greatest for people aged 30–39 years (27.5 million [95% CI, 16.0–41.0 million] hours; 26.9% of total labour loss) and people aged 40–49 years (24.5 million [95% CI, 12.1–38.7 million] hours; 23.9% of total labour loss). Conclusion Widespread SARS‐CoV‐2 infections in Australia mean that even a small proportion of infected people developing long COVID‐related illness and disability could have important population health and economic effects. 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Study design Modelling study: a susceptible–exposed–infected–recovered (SEIR) model to estimate the number of people with long COVID over time following single infections, and a labour supply model to estimate productivity losses as a proportion of gross domestic product (GDP). Setting Australia, 2022–2024. Main outcome measures Estimated number of people infected with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) during 2022–2023 (based on serosurvey data) who have long COVID, 2022–2024, by age group; estimated GDP loss during 2022 caused by reduced labour supply attributable to long COVID. Results Our model projected that the number of people with long COVID following a single infection in 2022 would peak in September 2022, when 310 341–1 374 805 people (1.2–5.4% of Australians) would have symptoms of long COVID, declining to 172 530–872 799 people (0.7–3.4%) in December 2024, including 7902–30 002 children aged 0–4 years (0.6–2.2%). The estimated mean labour loss attributable to long COVID in 2022 was projected to be 102.4 million (95% confidence interval [CI], 50.4–162.2 million) worked hours, equivalent to 0.48% (95% CI, 0.24–0.76%) of total worked hours in Australia during the 2020–21 financial year. The estimated mean GDP loss caused by the projected decline in labour supply and reduced use of other production factors was $9.6 billion (95% CI, $4.7–15.2 billion), or 0.5% of GDP. The estimated labour loss was greatest for people aged 30–39 years (27.5 million [95% CI, 16.0–41.0 million] hours; 26.9% of total labour loss) and people aged 40–49 years (24.5 million [95% CI, 12.1–38.7 million] hours; 23.9% of total labour loss). Conclusion Widespread SARS‐CoV‐2 infections in Australia mean that even a small proportion of infected people developing long COVID‐related illness and disability could have important population health and economic effects. A paradigm shift is needed, from a sole focus on the immediate effects of coronavirus disease 2019 (COVID‐19) to preventing and treating COVID‐19 and treating long COVID, with implications for vaccine and antiviral policy and other mitigation of COVID‐19.</abstract><cop>Australia</cop><pmid>39154292</pmid><doi>10.5694/mja2.52400</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-6017-4430</orcidid><oa>free_for_read</oa></addata></record>
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subjects Adolescent
Adult
Aged
Australia - epidemiology
Child
Child, Preschool
Cost of Illness
COVID-19 - economics
COVID-19 - epidemiology
Female
Gross Domestic Product
Humans
Infant
Infant, Newborn
Male
Middle Aged
Post-Acute COVID-19 Syndrome
Public Health - economics
SARS-CoV-2
Young Adult
title The public health and economic burden of long COVID in Australia, 2022–24: a modelling study
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