Synergism of colistin and globular endolysins against multidrug-resistant gram-negative bacteria

Endolysins (lysins), a novel class of antibacterial agents derived from bacteriophages, efficiently lyse bacteria by degrading the peptidoglycan layer within the bacterial wall. Colistin, a classic peptide antibiotic with the ability to permeabilize the outer membrane, has recently shown great promi...

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Veröffentlicht in:	International journal of biological macromolecules 2024-10, Vol.278 (Pt 2), p.134670, Article 134670
Hauptverfasser:	Zhang, Pengfei, Zeng, Ping, Lai, Christopher K.C., Ip, Margaret, To, Kenneth K.W., Zuo, Zhong, Xia, Jiang, Leung, Sharon S.Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Cell Line Colistin Colistin - pharmacology Drug Resistance, Multiple, Bacterial Drug Synergism Endolysin Endopeptidases - pharmacology Gram-negative bacteria Gram-Negative Bacteria - drug effects Humans
Online-Zugang:	Volltext
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