Altered purine and pentose phosphate pathway metabolism in uteroplacental insufficiency-induced intrauterine growth restriction offspring rats impair intestinal function

•IUGR neonates show unique gut dysfunction linked to metabolism.•Pentose phosphate pathway disruption linked to intestinal issues in IUGR.•Early biomarkers of IUGR intestinal issues identified through metabolomics. This study aimed to identify metabolic alterations in the small intestine of newborn...

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