β-Adrenergic blockade attenuates adverse adipose tissue responses after burn

Severe burn injuries are defined by a prolonged hypermetabolic response characterized by increases in resting energy expenditure, systemic catabolism, and multi-organ dysfunction. The sustained elevation of catecholamines following a burn injury is thought to significantly contribute to this hyperme...

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Veröffentlicht in:	Journal of molecular medicine (Berlin, Germany) Germany), 2024-10, Vol.102 (10), p.1245-1254
Hauptverfasser:	Bieerkehazhi, Shayahati, Abdullahi, Abdikarim, Khalaf, Fadi, Barayan, Dalia, de Brito Monteiro, Lauar, Samadi, Osai, Rix, Graham, Jeschke, Marc G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Adipose Tissue - drug effects Adipose Tissue - metabolism Adipose Tissue, White - drug effects Adipose Tissue, White - metabolism Adrenergic beta-Antagonists - pharmacology Adrenergic beta-Antagonists - therapeutic use Adrenergic receptors Animal models Animals Biomedical and Life Sciences Biomedicine Body fat Burn patients Burns Burns - drug therapy Burns - metabolism Catecholamines Disease Models, Animal Endoplasmic reticulum Endoplasmic Reticulum Stress - drug effects Energy expenditure Energy Metabolism - drug effects Human Genetics Internal Medicine Lipolysis Lipolysis - drug effects Male Mice Mice, Inbred C57BL Molecular Medicine Original Article Pediatrics Propranolol Propranolol - pharmacology Propranolol - therapeutic use Thermal injury
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