Recent advances in nanostructured delivery systems for vancomycin
Despite the development of new generations of antibiotics, vancomycin remained as a high-efficacy antibiotic for treating the infections caused by MRSA. Researchers have explored various nanoformulations, aiming to enhance the therapeutic efficacy of vancomycin. Such novel formulations improve the e...
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Veröffentlicht in: | Nanomedicine (London, England) England), 2024, Vol.19 (23), p.1931-1951 |
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container_end_page | 1951 |
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container_issue | 23 |
container_start_page | 1931 |
container_title | Nanomedicine (London, England) |
container_volume | 19 |
creator | Ansari, Mohabbat Shahlaei, Mohsen Hosseinzadeh, Simzar Moradi, Sajad |
description | Despite the development of new generations of antibiotics, vancomycin remained as a high-efficacy antibiotic for treating the infections caused by MRSA. Researchers have explored various nanoformulations, aiming to enhance the therapeutic efficacy of vancomycin. Such novel formulations improve the effectiveness of drug cargoes in treating bacterial infections and minimizing the risk of adverse effects. The vast of researches have focuses on enhancing the permeation ability of vancomycin through different biological barriers especially those of gastrointestinal tract. Increasing the drug loading and tuning the drug release from nanocarrier are other important goal for many conducted studies. This study reviews the newest nano-based formulations for vancomycin as a key antibiotic in treating hospitalized bacterial infections. |
doi_str_mv | 10.1080/17435889.2024.2377063 |
format | Article |
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subjects | Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Drug Carriers - chemistry Drug Delivery Systems - methods Drug Liberation Humans Methicillin-Resistant Staphylococcus aureus - drug effects Nanostructures - chemistry Staphylococcal Infections - drug therapy Vancomycin - administration & dosage Vancomycin - chemistry |
title | Recent advances in nanostructured delivery systems for vancomycin |
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