Recent advances in nanostructured delivery systems for vancomycin

Despite the development of new generations of antibiotics, vancomycin remained as a high-efficacy antibiotic for treating the infections caused by MRSA. Researchers have explored various nanoformulations, aiming to enhance the therapeutic efficacy of vancomycin. Such novel formulations improve the e...

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Veröffentlicht in:Nanomedicine (London, England) England), 2024, Vol.19 (23), p.1931-1951
Hauptverfasser: Ansari, Mohabbat, Shahlaei, Mohsen, Hosseinzadeh, Simzar, Moradi, Sajad
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container_end_page 1951
container_issue 23
container_start_page 1931
container_title Nanomedicine (London, England)
container_volume 19
creator Ansari, Mohabbat
Shahlaei, Mohsen
Hosseinzadeh, Simzar
Moradi, Sajad
description Despite the development of new generations of antibiotics, vancomycin remained as a high-efficacy antibiotic for treating the infections caused by MRSA. Researchers have explored various nanoformulations, aiming to enhance the therapeutic efficacy of vancomycin. Such novel formulations improve the effectiveness of drug cargoes in treating bacterial infections and minimizing the risk of adverse effects. The vast of researches have focuses on enhancing the permeation ability of vancomycin through different biological barriers especially those of gastrointestinal tract. Increasing the drug loading and tuning the drug release from nanocarrier are other important goal for many conducted studies. This study reviews the newest nano-based formulations for vancomycin as a key antibiotic in treating hospitalized bacterial infections.
doi_str_mv 10.1080/17435889.2024.2377063
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subjects Animals
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Drug Carriers - chemistry
Drug Delivery Systems - methods
Drug Liberation
Humans
Methicillin-Resistant Staphylococcus aureus - drug effects
Nanostructures - chemistry
Staphylococcal Infections - drug therapy
Vancomycin - administration & dosage
Vancomycin - chemistry
title Recent advances in nanostructured delivery systems for vancomycin
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