Vaccination to Prevent Lyme Disease: A Movement Towards Anti-Tick Approaches

Abstract Lyme disease is caused by the spirochete, Borrelia burgdorferi, which is transmitted by Ixodes spp ticks. The rise in Lyme disease cases since its discovery in the 1970s has reinforced the need for a vaccine. A vaccine based on B burgdorferi outer surface protein A (OspA) was approved by th...

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Veröffentlicht in:	The Journal of infectious diseases 2024-08, Vol.230 (Supplement_1), p.S82-S86
Hauptverfasser:	Johnson, Emily E, Hart, Thomas M, Fikrig, Erol
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Surface - immunology Bacterial Outer Membrane Proteins - immunology Bacterial Vaccines - administration & dosage Bacterial Vaccines - immunology Borrelia burgdorferi - immunology Disease transmission Humans Ixodes - microbiology Lipoproteins - immunology Lyme disease Lyme Disease - immunology Lyme Disease - prevention & control Lyme Disease Vaccines - immunology OspA protein Outer surface protein A Pathogens Spirochetes Surface protein A Vaccination Vaccines
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