Generation of an Armcx1 Conditional Knockout Mouse

ABSTRACT Armadillo repeat‐containing X‐linked protein‐1 (Armcx1) is a poorly characterized transmembrane protein that regulates mitochondrial transport in neurons. Its overexpression has been shown to induce neurite outgrowth in embryonic neurons and to promote retinal ganglion cell (RGC) survival a...

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Veröffentlicht in:	Genesis (New York, N.Y. : 2000) N.Y. : 2000), 2024-08, Vol.62 (4), p.e23615-n/a
Hauptverfasser:	Bright, Cora L., Bomze, Howard M., Bhaumik, Mantu, Kay, Jeremy N., Cartoni, Romain, Gospe, Sidney M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Animals Armadillo Domain Proteins - genetics Armadillo Domain Proteins - metabolism armadillo repeat‐containing X‐linked protein‐1 Axonal transport Axonogenesis conditional knockout Cre recombinase Crush tests Degeneration Deletion Environmental stress Gene deletion Mice Mice, Knockout mitochondria Morphology Nerves Neurons Optic nerve Optic Nerve - metabolism Protein transport Proteins Regrowth Retina Retina - metabolism retinal ganglion cell Retinal ganglion cells Retinal Ganglion Cells - metabolism SIX gene family
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