Cardiovascular health, polygenic risk score, and cancer risk: a prospective cohort study

Cancer and cardiovascular disease share common lifestyle risk factors. However, it remains unclear whether cardiovascular health (CVH) evaluated by Life’s Essential 8 can predict cancer risk, and attenuate the influence of genetic susceptibility on cancer. We aimed to evaluate independent and joint...

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Veröffentlicht in:	The American journal of clinical nutrition 2024-10, Vol.120 (4), p.785-793
Hauptverfasser:	Peng, Yu, Wang, Peng, Du, Han, Liu, Fubin, Wang, Xixuan, Si, Changyu, Gong, Jianxiao, Zhou, Huijun, Chen, Kexin, Song, Fangfang
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood pressure Body mass index Body size Cancer Cardiovascular diseases cardiovascular health Cohort analysis Confidence intervals Digestive system genetic predisposition Genome-wide association studies Hazard assessment Hazard identification Health risks Life’s Essential 8 Lipids Nucleotides Physical activity Population genetics Population studies Risk factors Single-nucleotide polymorphism UK Biobank Uterine cancer
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