Association of adiponectin gene single nucleotide polymorphisms with environmental risk factors in type 2 diabetes mellitus: An updated evidence of haplotype-based analysis study

•Haplotype-based analysis offers better insight into genetic diversity and disease associations than individual SNPs.•Combined haplotypes of the ADIPOQ gene significantly associate with plasma adiponectin concentration in healthy individuals.•Adiponectin levels in T2DM patients are lower than in hea...

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Veröffentlicht in:	Gene 2025-01, Vol.933, p.148816, Article 148816
Hauptverfasser:	Mamashli, Elahe, Goulding, Richie P., Iranparvar, Manouchehr, Skishahr, Farnaz Seifi, Siahkouhian, Marefat, Ramezanzade, Raziye, Jaspers, Richard T., Davarnia, Behzad
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin Adiponectin - genetics Adult Aged Case-Control Studies Cross-Sectional Studies Diabetes Mellitus, Type 2 - genetics Female Genetic Association Studies Genetic Predisposition to Disease Haplotype Haplotypes Humans Iran Male Middle Aged Polymorphism, Single Nucleotide Receptors, Adiponectin - genetics Risk Factors Single nucleotide polymorphism Type 2 diabetes mellitus
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