Bioactive polymers: A comprehensive review on bone grafting biomaterials

The application of bone grafting materials in bone tissue engineering is paramount for treating severe bone defects. In this comprehensive review, we explore the significance and novelty of utilizing bioactive polymers as grafts for successful bone repair. Unlike metals and ceramics, polymers offer...

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Veröffentlicht in:International journal of biological macromolecules 2024-10, Vol.278 (Pt 2), p.134615, Article 134615
Hauptverfasser: Pourhajrezaei, Sana, Abbas, Zahid, Khalili, Mohammad Amin, Madineh, Hossein, Jooya, Hossein, Babaeizad, Ali, Gross, Jeffrey D., Samadi, Ali
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container_end_page
container_issue Pt 2
container_start_page 134615
container_title International journal of biological macromolecules
container_volume 278
creator Pourhajrezaei, Sana
Abbas, Zahid
Khalili, Mohammad Amin
Madineh, Hossein
Jooya, Hossein
Babaeizad, Ali
Gross, Jeffrey D.
Samadi, Ali
description The application of bone grafting materials in bone tissue engineering is paramount for treating severe bone defects. In this comprehensive review, we explore the significance and novelty of utilizing bioactive polymers as grafts for successful bone repair. Unlike metals and ceramics, polymers offer inherent biodegradability and biocompatibility, mimicking the native extracellular matrix of bone. While these polymeric micro-nano materials may face challenges such as mechanical strength, various fabrication techniques are available to overcome these shortcomings. Our study not only investigates diverse biopolymeric materials but also illuminates innovative fabrication methods, highlighting their importance in advancing bone tissue engineering. [Display omitted]
doi_str_mv 10.1016/j.ijbiomac.2024.134615
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source Elsevier ScienceDirect Journals
subjects Biomedical applications
Bone tissue engineering
Polymeric biomaterials
title Bioactive polymers: A comprehensive review on bone grafting biomaterials
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