Reduction in neurons immunoreactive for calcium-binding proteins in the anteroventral thalamic nuclei of individuals with Down syndrome

•The anteroventral thalamic nucleus was assessed in individuals with Down syndrome.•There was increased beta-amyloid plaque expression in the AV in the Down syndrome group.•The proportion of CBP-immunopositive cells was reduced in the AV in Down syndrome. The anterior thalamic nuclei are important f...

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Veröffentlicht in:	Neuroscience 2024-10, Vol.557, p.56-66
Hauptverfasser:	Perry, James C., Vann, Seralynne D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer’s disease Amyloid Anterior thalamic nuclei Calbindin Calretinin Immunohistochemistry Parvalbumin
Online-Zugang:	Volltext
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