Peroxiporins and Oxidative Stress: Promising Targets to Tackle Inflammation and Cancer

Peroxiporins are a specialized subset of aquaporins, which are integral membrane proteins primarily known for facilitating water transport across cell membranes. In addition to the classical water transport function, peroxiporins have the unique capability to transport hydrogen peroxide (H O ), a re...

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Veröffentlicht in:	International journal of molecular sciences 2024-08, Vol.25 (15), p.8381
Hauptverfasser:	da Silva, Inês V, Mlinarić, Monika, Lourenço, Ana Rita, Pérez-Garcia, Olivia, Čipak Gašparović, Ana, Soveral, Graça
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aquaporins Aquaporins - metabolism Cancer Cancer therapies Cell growth Defense mechanisms Development and progression Endoplasmic reticulum Glycerol Humans Hydrogen bonds Hydrogen Peroxide - metabolism Inflammation Inflammation - metabolism Kinases Membranes Mutation Neoplasms - metabolism Oxidation-Reduction Oxidative Stress Permeability Physiological aspects Protein folding Reactive oxygen species Reactive Oxygen Species - metabolism Signal Transduction Type 2 diabetes
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