HPV- associated sinonasal squamous cell carcinoma with FGFR3::TACC3 fusion. A rare case report

Sinonasal squamous cell carcinomas (SNSCCs) are uncommon and they are associated with adverse prognosis. HPV-associated SNSCCs and fusion-driven SNSCCs are particularly rare. A case of an HPV-associated SNSCC with a FGFR3::TACC3 fusion is thus presented; a brief review of the pertinent literature is...

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Veröffentlicht in:Oral oncology 2024-10, Vol.157, p.106983, Article 106983
Hauptverfasser: Tamiolakis, Paris, Shah, Alina, Dawson, Rebecca, Ramasamy, Satiavani, Hutchins, Gordon G.A.
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container_start_page 106983
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creator Tamiolakis, Paris
Shah, Alina
Dawson, Rebecca
Ramasamy, Satiavani
Hutchins, Gordon G.A.
description Sinonasal squamous cell carcinomas (SNSCCs) are uncommon and they are associated with adverse prognosis. HPV-associated SNSCCs and fusion-driven SNSCCs are particularly rare. A case of an HPV-associated SNSCC with a FGFR3::TACC3 fusion is thus presented; a brief review of the pertinent literature is also provided.
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subjects Carcinoma, Squamous Cell - genetics
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - virology
Female
FGFR3 fusion
HPV sinonasal cancer
HPV sinonasal squamous cell carcinoma
Humans
Male
Microtubule-Associated Proteins - genetics
Middle Aged
Papillomavirus Infections - complications
Papillomavirus Infections - virology
Paranasal Sinus Neoplasms - genetics
Paranasal Sinus Neoplasms - pathology
Paranasal Sinus Neoplasms - virology
Receptor, Fibroblast Growth Factor, Type 3 - genetics
Sinonasal cancer
Sinonasal squamous cell carcinoma
title HPV- associated sinonasal squamous cell carcinoma with FGFR3::TACC3 fusion. A rare case report
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