Emerging Therapeutic Targets and Future Directions in Advanced Gastric Cancer: A Comprehensive Review

Metastatic gastric cancer (GC) still represents a critical clinical challenge, with limited treatment options and a poor prognosis. Most patients are diagnosed at advanced stages, limiting the chances of surgery and cure. The identification of molecular targets and the possibility of combining immun...

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Veröffentlicht in:	Cancers 2024-08, Vol.16 (15), p.2692
Hauptverfasser:	Ratti, Margherita, Orlandi, Elena, Toscani, Ilaria, Vecchia, Stefano, Anselmi, Elisa, Hahne, Jens Claus, Ghidini, Michele, Citterio, Chiara
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Antimitotic agents Antineoplastic agents Apoptosis Cancer Cancer therapies Cancer vaccines Care and treatment Cell death Chemotherapy Chimeric antigen receptors Clinical trials Cytotoxicity Development and progression ErbB-2 protein Fibroblast growth factor receptors Fibroblast growth factors Gastric cancer Health aspects Immune checkpoint inhibitors Immune system Immunotherapy Kinases Lymphocytes T Medical prognosis Metastases Metastasis Microsatellite instability Oncology, Experimental Patients PD-1 protein Prognosis Response rates Stomach cancer T cells Therapeutic targets Trifluridine Tumors Vaccines
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