Basic Science and Pathogenesis - Part 2

Genetic studies of Alzheimer's disease (AD) have shown association with microglia in the brain. We probed microglia with markers against amyloid-associated (Clec7a, Axl), inflammatory M1 (CD86), alternatively activated M2 (CD206, CD163), and homeostatic (P2ry12, TMEM119) phenotypes in low plaqu...

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Veröffentlicht in:	Alzheimer's & dementia 2023-12, Vol.19 Suppl 13, p.e073956
Hauptverfasser:	Melnik, Mikhail, Bilousova, Tina, Ma, Ricky, Matsuo, Yuriko, Atluri, Swetha, Kodavatikanti, Achyutha, Knitowski, Nina, Gylys, Karen H
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - genetics Alzheimer Disease - pathology Antigens, CD - metabolism Antigens, Differentiation, Myelomonocytic - metabolism Apolipoproteins E - genetics Axl Receptor Tyrosine Kinase Brain - pathology Female Humans Male Membrane Proteins - genetics Membrane Proteins - metabolism Microglia - metabolism Microglia - pathology Plaque, Amyloid - pathology Receptors, Cell Surface - metabolism
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