Tumor microenvironment-modulated nanoparticles with cascade energy transfer as internal light sources for photodynamic therapy of deep-seated tumors

Photodynamic therapy (PDT) is an appealing modality for cancer treatments. However, the limited tissue penetration depth of external-excitation light makes PDT impossible in treating deep-seated tumors. Meanwhile, tumor hypoxia and intracellular reductive microenvironment restrain the generation of...

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Veröffentlicht in:	Biomaterials 2025-01, Vol.312, p.122743, Article 122743
Hauptverfasser:	Dai, Wenbin, Zhou, Xianchi, Zhao, Jinchao, Lei, Lei, Huang, Yue, Jia, Fan, Tang, Zhe, Ji, Jian, Jin, Qiao
Format:	Artikel
Sprache:	eng
Schlagworte:	Antitumor Chemiluminescence resonance energy transfer Nitric oxide Self-excited photodynamic therapy Tumor microenvironment modulation
Online-Zugang:	Volltext
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