A pre-vertebrate endodermal origin of calcitonin-producing neuroendocrine cells

Vertebrate calcitonin-producing cells (C-cells) are neuroendocrine cells that secrete the small peptide hormone calcitonin in response to elevated blood calcium levels. Whereas mouse C-cells reside within the thyroid gland and derive from pharyngeal endoderm, avian C-cells are located within ultimob...

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Veröffentlicht in:	Development (Cambridge) 2024-10, Vol.151 (20)
Hauptverfasser:	Rees, Jenaid M, Kirk, Katie, Gattoni, Giacomo, Hockman, Dorit, Sleight, Victoria A, Ritter, Dylan J, Benito-Gutierrez, Èlia, Knapik, Ela W, Crump, J Gage, Fabian, Peter, Gillis, J Andrew
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcitonin - metabolism Cell Lineage Chick Embryo Ciona intestinalis - embryology Ciona intestinalis - metabolism Endoderm - cytology Endoderm - metabolism Lancelets - embryology Lancelets - genetics Lancelets - metabolism Mice Neural Crest - cytology Neural Crest - metabolism Neuroendocrine Cells - cytology Neuroendocrine Cells - metabolism Ultimobranchial Body - metabolism Vertebrates - embryology Vertebrates - metabolism Zebrafish - embryology
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