Novel Antimitotic Agent SP-1-39 Inhibits Head and Neck Squamous Cell Carcinoma

Effective management of head and neck cancer (HNC) poses a significant challenge in the field of oncology, due to its intricate pathophysiology and limited treatment options. The most common HNC malignancy is head and neck squamous cell carcinoma (HNSCC). HNSCC treatment includes a combination of su...

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Veröffentlicht in:	Journal of dental research 2024-08, Vol.103 (9), p.926-936
Hauptverfasser:	Adeleye, K.L., Li, A.R., Xie, Y., Pochampally, S., Hamilton, D., Garcia-Godoy, F., Miller, D.D., Li, W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Antimitotic Agents - pharmacology Antimitotic Agents - therapeutic use Apoptosis Apoptosis - drug effects Cancer therapies Carcinoma, Squamous Cell - drug therapy Cell cycle Cell Line, Tumor Cell migration Cell proliferation Cell Proliferation - drug effects Chemotherapy Colchicine Cytotoxicity Disease management Head & neck cancer Head and neck carcinoma Head and Neck Neoplasms - drug therapy Humans Male Malignancy Melanoma Metastases Mice Paclitaxel Pancreas Pancreatic cancer Prostate Prostate cancer Squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck - drug therapy Tumor cell lines Xenograft Model Antitumor Assays Xenografts
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