Celiac plexus block: A diagnostic tool for neurogenic median arcuate ligament syndrome
Objective The objective of this study was to evaluate the effect of outpatient celiac plexus block on acute pain reduction in patients with suspected median arcuate ligament syndrome. Methods This is an Institutional Review Board approved, retrospective chart review. Data were collected and analyzed...
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description | Objective
The objective of this study was to evaluate the effect of outpatient celiac plexus block on acute pain reduction in patients with suspected median arcuate ligament syndrome.
Methods
This is an Institutional Review Board approved, retrospective chart review. Data were collected and analyzed from patients who received celiac plexus blocks from November 1, 2021 through April 6, 2023. The primary outcome was pain reduction, determined by the change in numerical pain rating scale (NPRS) from pre‐procedure to post‐procedure. Additional data collected include patient demographics, comorbidities, preoperative symptoms and duration of symptoms.
Results
There were 33 patients identified in this study. Thirty‐one patients were included in the data analysis. The median age of the cohort was 29 years, and the median BMI was 20.4. 94% of the cohort was female. These patients were referred as part of an evaluation for symptomatic vascular compression disorders. For many patients, positive response to celiac plexus block was used as an indication to proceed with surgical MALS resection. We provide a diagnostic algorithm for MALs. All patients endorsed preoperative symptoms. Patients experienced a median pain reduction of −4 from baseline to immediately post‐procedure.
Conclusions
Celiac plexus blocks continue to be a tool for ruling out neurogenic median arcuate ligament syndrome in patients who have undergone extensive previous imaging and assessments for vascular compression disorders. Our data suggest that patients with suspected MALS may experience substantial immediate pain relief from temporary blocks of the celiac ganglion as guided by fluoroscopy in an outpatient setting. |
doi_str_mv | 10.1111/papr.13403 |
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The objective of this study was to evaluate the effect of outpatient celiac plexus block on acute pain reduction in patients with suspected median arcuate ligament syndrome.
Methods
This is an Institutional Review Board approved, retrospective chart review. Data were collected and analyzed from patients who received celiac plexus blocks from November 1, 2021 through April 6, 2023. The primary outcome was pain reduction, determined by the change in numerical pain rating scale (NPRS) from pre‐procedure to post‐procedure. Additional data collected include patient demographics, comorbidities, preoperative symptoms and duration of symptoms.
Results
There were 33 patients identified in this study. Thirty‐one patients were included in the data analysis. The median age of the cohort was 29 years, and the median BMI was 20.4. 94% of the cohort was female. These patients were referred as part of an evaluation for symptomatic vascular compression disorders. For many patients, positive response to celiac plexus block was used as an indication to proceed with surgical MALS resection. We provide a diagnostic algorithm for MALs. All patients endorsed preoperative symptoms. Patients experienced a median pain reduction of −4 from baseline to immediately post‐procedure.
Conclusions
Celiac plexus blocks continue to be a tool for ruling out neurogenic median arcuate ligament syndrome in patients who have undergone extensive previous imaging and assessments for vascular compression disorders. Our data suggest that patients with suspected MALS may experience substantial immediate pain relief from temporary blocks of the celiac ganglion as guided by fluoroscopy in an outpatient setting.</description><identifier>ISSN: 1530-7085</identifier><identifier>ISSN: 1533-2500</identifier><identifier>EISSN: 1533-2500</identifier><identifier>DOI: 10.1111/papr.13403</identifier><identifier>PMID: 39099243</identifier><language>eng</language><publisher>United States</publisher><subject>Adolescent ; Adult ; Autonomic Nerve Block - methods ; Celiac Plexus ; celiac plexus block (CPB) ; Female ; Humans ; Male ; median arcuate ligament syndrome (MALS) ; Median Arcuate Ligament Syndrome - surgery ; Middle Aged ; Pain Measurement - methods ; Retrospective Studies ; Young Adult</subject><ispartof>Pain practice, 2025-01, Vol.25 (1), p.e13403-n/a</ispartof><rights>2024 World Institute of Pain.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c2183-76f1a55f7a81e8ed0c68c57f66d2c21bc300780daa22bf38000d877c3766a2093</cites><orcidid>0009-0008-2894-2960 ; 0000-0001-6870-9436</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fpapr.13403$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fpapr.13403$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39099243$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bower, Kathryn S.</creatorcontrib><creatorcontrib>McCarthy, Chloe C.</creatorcontrib><creatorcontrib>Vyasa, Parth</creatorcontrib><creatorcontrib>Nagarsheth, Khanjan</creatorcontrib><creatorcontrib>Desai, Mehul J.</creatorcontrib><title>Celiac plexus block: A diagnostic tool for neurogenic median arcuate ligament syndrome</title><title>Pain practice</title><addtitle>Pain Pract</addtitle><description>Objective
The objective of this study was to evaluate the effect of outpatient celiac plexus block on acute pain reduction in patients with suspected median arcuate ligament syndrome.
Methods
This is an Institutional Review Board approved, retrospective chart review. Data were collected and analyzed from patients who received celiac plexus blocks from November 1, 2021 through April 6, 2023. The primary outcome was pain reduction, determined by the change in numerical pain rating scale (NPRS) from pre‐procedure to post‐procedure. Additional data collected include patient demographics, comorbidities, preoperative symptoms and duration of symptoms.
Results
There were 33 patients identified in this study. Thirty‐one patients were included in the data analysis. The median age of the cohort was 29 years, and the median BMI was 20.4. 94% of the cohort was female. These patients were referred as part of an evaluation for symptomatic vascular compression disorders. For many patients, positive response to celiac plexus block was used as an indication to proceed with surgical MALS resection. We provide a diagnostic algorithm for MALs. All patients endorsed preoperative symptoms. Patients experienced a median pain reduction of −4 from baseline to immediately post‐procedure.
Conclusions
Celiac plexus blocks continue to be a tool for ruling out neurogenic median arcuate ligament syndrome in patients who have undergone extensive previous imaging and assessments for vascular compression disorders. Our data suggest that patients with suspected MALS may experience substantial immediate pain relief from temporary blocks of the celiac ganglion as guided by fluoroscopy in an outpatient setting.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Autonomic Nerve Block - methods</subject><subject>Celiac Plexus</subject><subject>celiac plexus block (CPB)</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>median arcuate ligament syndrome (MALS)</subject><subject>Median Arcuate Ligament Syndrome - surgery</subject><subject>Middle Aged</subject><subject>Pain Measurement - methods</subject><subject>Retrospective Studies</subject><subject>Young Adult</subject><issn>1530-7085</issn><issn>1533-2500</issn><issn>1533-2500</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2025</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF1LwzAUQIMobk5f_AGSRxE6b5qlSX0bwy8YOER9LWmajmra1KRF9-_N1umjebnhcjhwD0LnBKYkvOtWtm5K6AzoARoTRmkUM4DD3R8iDoKN0In37wCEp5QeoxFNIU3jGR2jt4U2lVS4Nfq79zg3Vn3c4DkuKrlurO8qhTtrDS6tw43unV3rJuxqHYAGS6d62WlsqrWsddNhv2kKZ2t9io5Kabw-288Jer27fVk8RMun-8fFfBmpmAga8aQkkrGSS0G00AWoRCjGyyQp4kDkigJwAYWUcZyXVABAIThXlCeJjCGlE3Q5eFtnP3vtu6yuvNLGyEbb3mcUhGBsBjMW0KsBVc5673SZta6qpdtkBLJtx2zbMdt1DPDF3tvn4dY_9DdcAMgAfFVGb_5RZav56nmQ_gCk7X1J</recordid><startdate>202501</startdate><enddate>202501</enddate><creator>Bower, Kathryn S.</creator><creator>McCarthy, Chloe C.</creator><creator>Vyasa, Parth</creator><creator>Nagarsheth, Khanjan</creator><creator>Desai, Mehul J.</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0009-0008-2894-2960</orcidid><orcidid>https://orcid.org/0000-0001-6870-9436</orcidid></search><sort><creationdate>202501</creationdate><title>Celiac plexus block: A diagnostic tool for neurogenic median arcuate ligament syndrome</title><author>Bower, Kathryn S. ; McCarthy, Chloe C. ; Vyasa, Parth ; Nagarsheth, Khanjan ; Desai, Mehul J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2183-76f1a55f7a81e8ed0c68c57f66d2c21bc300780daa22bf38000d877c3766a2093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2025</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Autonomic Nerve Block - methods</topic><topic>Celiac Plexus</topic><topic>celiac plexus block (CPB)</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>median arcuate ligament syndrome (MALS)</topic><topic>Median Arcuate Ligament Syndrome - surgery</topic><topic>Middle Aged</topic><topic>Pain Measurement - methods</topic><topic>Retrospective Studies</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bower, Kathryn S.</creatorcontrib><creatorcontrib>McCarthy, Chloe C.</creatorcontrib><creatorcontrib>Vyasa, Parth</creatorcontrib><creatorcontrib>Nagarsheth, Khanjan</creatorcontrib><creatorcontrib>Desai, Mehul J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pain practice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bower, Kathryn S.</au><au>McCarthy, Chloe C.</au><au>Vyasa, Parth</au><au>Nagarsheth, Khanjan</au><au>Desai, Mehul J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Celiac plexus block: A diagnostic tool for neurogenic median arcuate ligament syndrome</atitle><jtitle>Pain practice</jtitle><addtitle>Pain Pract</addtitle><date>2025-01</date><risdate>2025</risdate><volume>25</volume><issue>1</issue><spage>e13403</spage><epage>n/a</epage><pages>e13403-n/a</pages><issn>1530-7085</issn><issn>1533-2500</issn><eissn>1533-2500</eissn><abstract>Objective
The objective of this study was to evaluate the effect of outpatient celiac plexus block on acute pain reduction in patients with suspected median arcuate ligament syndrome.
Methods
This is an Institutional Review Board approved, retrospective chart review. Data were collected and analyzed from patients who received celiac plexus blocks from November 1, 2021 through April 6, 2023. The primary outcome was pain reduction, determined by the change in numerical pain rating scale (NPRS) from pre‐procedure to post‐procedure. Additional data collected include patient demographics, comorbidities, preoperative symptoms and duration of symptoms.
Results
There were 33 patients identified in this study. Thirty‐one patients were included in the data analysis. The median age of the cohort was 29 years, and the median BMI was 20.4. 94% of the cohort was female. These patients were referred as part of an evaluation for symptomatic vascular compression disorders. For many patients, positive response to celiac plexus block was used as an indication to proceed with surgical MALS resection. We provide a diagnostic algorithm for MALs. All patients endorsed preoperative symptoms. Patients experienced a median pain reduction of −4 from baseline to immediately post‐procedure.
Conclusions
Celiac plexus blocks continue to be a tool for ruling out neurogenic median arcuate ligament syndrome in patients who have undergone extensive previous imaging and assessments for vascular compression disorders. Our data suggest that patients with suspected MALS may experience substantial immediate pain relief from temporary blocks of the celiac ganglion as guided by fluoroscopy in an outpatient setting.</abstract><cop>United States</cop><pmid>39099243</pmid><doi>10.1111/papr.13403</doi><tpages>9</tpages><orcidid>https://orcid.org/0009-0008-2894-2960</orcidid><orcidid>https://orcid.org/0000-0001-6870-9436</orcidid></addata></record> |
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source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
subjects | Adolescent Adult Autonomic Nerve Block - methods Celiac Plexus celiac plexus block (CPB) Female Humans Male median arcuate ligament syndrome (MALS) Median Arcuate Ligament Syndrome - surgery Middle Aged Pain Measurement - methods Retrospective Studies Young Adult |
title | Celiac plexus block: A diagnostic tool for neurogenic median arcuate ligament syndrome |
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