The unique metabolome of clear cell ovarian carcinoma

Clear cell ovarian carcinoma (CCOC) is an aggressive malignancy affecting younger women. Despite ovarian cancer subtypes having diverse molecular and clinical characteristics, the mainstay of treatment for advanced stage disease remains cytotoxic chemotherapy. Late stage CCOC is resistant to convent...

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Veröffentlicht in:	The Journal of pathology 2024-10, Vol.264 (2), p.160-173
Hauptverfasser:	Ji, Jennifer X, Hoang, Lien N, Cochrane, Dawn R, Lum, Amy, Senz, Janine, Farnell, David, Tessier‐Cloutier, Basile, Huntsman, David G, Klein Geltink, Ramon I
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemotherapy clear cell ovarian carcinoma Cytotoxicity Energy metabolism Glycogen Malignancy Metabolic pathways Metabolism Metabolomics Ovarian cancer Ovarian carcinoma Patients Proteomics Therapeutic targets Transcriptomics
Online-Zugang:	Volltext
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