Wnt/β-Catenin–Activated Nonpilomatrical Carcinoma of the Skin: A Case Series

Among skin epithelial tumors, recurrent mutations in the APC/CTNNB1 genes resulting in activation of the Wnt/β-catenin pathway have been reported predominantly in neoplasms with matrical differentiation. In the present study, we describe the morphologic, immunohistochemical, and genetic features of...

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Veröffentlicht in:	Modern pathology 2024-11, Vol.37 (11), p.100586, Article 100586
Hauptverfasser:	Kervarrec, Thibault, Cheok Lei, Kuan, Sohier, Pierre, Macagno, Nicolas, Jullie, Marie-Laure, Frouin, Eric, Goto, Keisuke, Taniguchi, Kohei, Hamard, Aymeric, Taillandier, Antoine, Tallet, Anne, Bonenfant, Christine, Sahin, Yusuf, Barry, Fatoumata, Taibjee, Saleem, Cokelaere, Kristof, Houben, Roland, Schrama, David, Nardin, Charlee, Aubin, Francois, Doucet, Laurent, Pissaloux, Daniel, Tirode, Franck, Fouchardière, Arnaud de la, Balme, Brigitte, Laurent-Roussel, Sara, Becker, Jürgen C., von Deimling, Andreas, Samimi, Mahtab, Cribier, Bernard, Battistella, Maxime, Calonje, Eduardo, Guyétan, Serge
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over beta Catenin - genetics beta Catenin - metabolism Biomarkers, Tumor - analysis Biomarkers, Tumor - genetics carcinoma Carcinoma, Merkel Cell - genetics Carcinoma, Merkel Cell - metabolism Carcinoma, Merkel Cell - pathology CDX2 Female Humans Immunohistochemistry Male matrical Merkel Middle Aged Mutation Pilomatrixoma - genetics Pilomatrixoma - metabolism Pilomatrixoma - pathology skin Skin Neoplasms - genetics Skin Neoplasms - metabolism Skin Neoplasms - pathology Wnt Signaling Pathway - genetics Wnt Signaling Pathway - physiology β-catenin
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