Risk of acute kidney injury after lower urinary tract reconstruction with early NSAID therapy: A propensity matched retrospective analysis

The opioid epidemic response led to increased use of postoperative, non-opioid analgesia. Some pediatric urologists do not routinely use non-steroidal anti-inflammatory drugs (NSAIDs) for fear of causing acute kidney injury (AKI). While previous studies have demonstrated the safety and efficacy of N...

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Veröffentlicht in:	Journal of pediatric urology 2024-10, Vol.20 (5), p.911-920
Hauptverfasser:	Ha, Darren, Halstead, N. Valeska, Blanchette, Eliza D., Wilcox, Duncan T., Vemulakonda, Vijaya M., Wood, Daniel N., Rove, Kyle O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute kidney injury Acute Kidney Injury - chemically induced Acute Kidney Injury - epidemiology Acute Kidney Injury - etiology Adolescent Anti-Inflammatory Agents, Non-Steroidal - adverse effects Child Child, Preschool Female Humans Incidence Lower urinary tract reconstruction Male Non-steroidal anti-inflammatory Opioid reduction Plastic Surgery Procedures - adverse effects Plastic Surgery Procedures - methods Postoperative Complications - epidemiology Propensity Score Retrospective Studies Risk Assessment Urologic Surgical Procedures - adverse effects Urologic Surgical Procedures - methods
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Zusammenfassung:	The opioid epidemic response led to increased use of postoperative, non-opioid analgesia. Some pediatric urologists do not routinely use non-steroidal anti-inflammatory drugs (NSAIDs) for fear of causing acute kidney injury (AKI). While previous studies have demonstrated the safety and efficacy of NSAIDs in children, safety after lower urinary tract reconstruction has not been well characterized. ptUsing the Kidney Disease: Improving Global Outcomes (KDIGO) criteria for AKI (increase in creatinine ≥0.3 mg/dL or increase in creatinine ≥1.5x baseline or urine output
ISSN:	1477-5131 1873-4898 1873-4898
DOI:	10.1016/j.jpurol.2024.07.005